Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GRPR
  • Mouse genes Grpr
  • Rat genes Grpr
  • Zfish genes grpr
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Grpr

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008528	G protein-coupled peptide receptor activity	GRPR	IDA		Human	PMID:1655761
Molecular Function	GO:0008528	G protein-coupled peptide receptor activity	Grpr	IDA		Mouse	MGI:MGI:76127|PMID:1671171
Molecular Function	GO:0004930	G protein-coupled receptor activity	Grpr	IDA		Rat	PMID:2542758|RGD:1641838
Molecular Function	GO:0042923	neuropeptide binding	Grpr	IDA		Rat	PMID:2542758|RGD:1641838
Molecular Function	GO:0008188	neuropeptide receptor activity	Grpr	IMP		Mouse	MGI:MGI:5704231|PMID:26658875
Molecular Function	GO:0005515	protein binding	Grpr	IPI	UniProtKB:P42866-9	Mouse	MGI:MGI:5295318|PMID:22000021
Cellular Component	GO:0016020	membrane	Grpr	IDA		Rat	PMID:2542758|RGD:1641838
Cellular Component	GO:0005886	plasma membrane	GRPR	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	GRPR	IMP		Human	PMID:1655761
Cellular Component	GO:0005886	plasma membrane	Grpr	IDA		Mouse	MGI:MGI:76127|PMID:1671171
Biological Process	GO:0007186	G protein-coupled receptor signaling pathway	Grpr	IDA		Rat	PMID:2542758|RGD:1641838
Biological Process	GO:0007611	learning or memory	Grpr	IMP		Rat	PMID:17097693|RGD:1641840
Biological Process	GO:0061744	motor behavior	Grpr	IMP		Mouse	MGI:MGI:5704231|PMID:26658875
Biological Process	GO:0007200	phospholipase C-activating G protein-coupled receptor signaling pathway	Grpr	IMP		Mouse	MGI:MGI:5704231|PMID:26658875
Biological Process	GO:2000987	positive regulation of behavioral fear response	Grpr	IMP		Mouse	MGI:MGI:6790352|PMID:34610277
Biological Process	GO:1903942	positive regulation of respiratory gaseous exchange	Grpr	IMP		Mouse	MGI:MGI:5751330|PMID:26855425
Biological Process	GO:0036343	psychomotor behavior	Grpr	IMP		Mouse	MGI:MGI:5887141|PMID:28280205
Biological Process	GO:0042127	regulation of cell population proliferation	Grpr	IMP	MGI:MGI:1857462	Mouse	PMID:11960700
Biological Process	GO:0043207	response to external biotic stimulus	Grpr	IMP		Mouse	MGI:MGI:5887141|PMID:28280205
Biological Process	GO:0035176	social behavior	Grpr	IMP		Mouse	MGI:MGI:5887141|PMID:28280205
Biological Process	GO:0035176	social behavior	Grpr	IMP		Rat	PMID:17097693|RGD:1641840

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern