Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GRM3
  • Mouse genes Grm3
  • Rat genes Grm3
  • Zfish genes grm3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Grm3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005246	calcium channel regulator activity	Grm3	IDA		Mouse	PMID:7965099
Molecular Function	GO:0001641	group II metabotropic glutamate receptor activity	Grm3	IDA		Mouse	PMID:7965099
Molecular Function	GO:0001641	group II metabotropic glutamate receptor activity	Grm3	IMP		Rat	PMID:12694929|RGD:1298935
Molecular Function	GO:0097110	scaffold protein binding	Grm3	IPI	UniProtKB:O14745	Rat	PMID:28392297|RGD:21201273
Molecular Function	GO:0097110	scaffold protein binding	Grm3	IPI	UniProtKB:Q8SQG9	Rat	PMID:28392297|RGD:21201273
Cellular Component	GO:0097449	astrocyte projection	Grm3	IDA		Rat	PMID:21753079|RGD:7207797
Cellular Component	GO:0097449	astrocyte projection	Grm3	IDA		Rat	PMID:28392297|RGD:21201273
Cellular Component	GO:0030424	axon	Grm3	IDA		Mouse	MGI:MGI:3688033|PMID:11591452
Cellular Component	GO:0030424	axon	Grm3	IDA		Rat	PMID:28392297|RGD:21201273
Cellular Component	GO:0043197	dendritic spine	Grm3	IDA		Mouse	MGI:MGI:3688033|PMID:11591452
Cellular Component	GO:0098978	glutamatergic synapse	Grm3	IDA		Mouse	PMID:11591452
Cellular Component	GO:0098978	glutamatergic synapse	Grm3	IDA		Mouse	PMID:31735403
Cellular Component	GO:0098978	glutamatergic synapse	Grm3	EXP		Mouse	PMID:31735403
Cellular Component	GO:0043005	neuron projection	Grm3	IDA		Mouse	PMID:12074840
Cellular Component	GO:0005886	plasma membrane	Grm3	IDA		Mouse	MGI:MGI:3688033|PMID:11591452
Cellular Component	GO:0098794	postsynapse	Grm3	IDA		Mouse	MGI:MGI:6386529|PMID:31735403
Cellular Component	GO:0014069	postsynaptic density	Grm3	IDA		Mouse	PMID:15579147
Cellular Component	GO:0045211	postsynaptic membrane	Grm3	IDA		Mouse	PMID:11591452
Cellular Component	GO:0042734	presynaptic membrane	Grm3	IDA		Mouse	PMID:11591452
Biological Process	GO:0033554	cellular response to stress	Grm3	IDA		Mouse	PMID:29024663
Biological Process	GO:0010467	gene expression	Grm3	IMP	MGI:MGI:5558949	Mouse	PMID:18720515
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Grm3	IDA		Rat	PMID:12694929|RGD:1298935
Biological Process	GO:0099170	postsynaptic modulation of chemical synaptic transmission	Grm3	EXP		Mouse	PMID:31735403
Biological Process	GO:0099170	postsynaptic modulation of chemical synaptic transmission	Grm3	IDA		Mouse	PMID:31735403

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern