Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GPR161
  • Mouse genes Gpr161
  • Rat genes Gpr161
  • Zfish genes gpr161a,gpr161b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gpr161

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004930	G protein-coupled receptor activity	Gpr161	IDA		Mouse	MGI:MGI:5468365|PMID:23332756
Molecular Function	GO:0005515	protein binding	GPR161	IPI	UniProtKB:O75841	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPR161	IPI	UniProtKB:P21964	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPR161	IPI	UniProtKB:P52803	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPR161	IPI	UniProtKB:Q8N6F1-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GPR161	IPI	UniProtKB:Q9BRI3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Gpr161	IPI	UniProtKB:P50607	Mouse	PMID:28154160
Molecular Function	GO:0005515	protein binding	Gpr161	IPI	UniProtKB:O75386	Mouse	PMID:28154160
Cellular Component	GO:0005929	cilium	Gpr161	IDA		Mouse	MGI:MGI:5468365|PMID:23332756
Cellular Component	GO:0005929	cilium	Gpr161	IDA		Mouse	PMID:28154160
Cellular Component	GO:0097386	glial cell projection	Gpr161	IDA		Mouse	PMID:28154160
Cellular Component	GO:0043005	neuron projection	Gpr161	IDA		Mouse	PMID:28154160
Cellular Component	GO:0055037	recycling endosome	Gpr161	IDA		Mouse	MGI:MGI:5468365|PMID:23332756
Biological Process	GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway	Gpr161	IDA		Mouse	MGI:MGI:5468365|PMID:23332756
Biological Process	GO:0007368	determination of left/right symmetry	gpr161b	IMP	ZFIN:ZDB-MRPHLNO-090206-6	Zfish	PMID:18755178
Biological Process	GO:0007368	determination of left/right symmetry	gpr161b	IMP	ZFIN:ZDB-MRPHLNO-090206-5	Zfish	PMID:18755178
Biological Process	GO:1901621	negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning	Gpr161	IMP		Mouse	MGI:MGI:5468365|PMID:23332756
Biological Process	GO:0051924	regulation of calcium ion transport	gpr161b	IMP	ZFIN:ZDB-MRPHLNO-090206-5	Zfish	PMID:18755178

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern