Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GMEB1
  • Mouse genes Gmeb1
  • Rat genes Gmeb1
  • Zfish genes gmeb1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gmeb1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Gmeb1	IDA		Mouse	MGI:MGI:1934160|PMID:10692587
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Gmeb1	IDA		Mouse	PMID:10692587
Molecular Function	GO:0051008	Hsp27 protein binding	GMEB1	IPI	UniProtKB:P04792	Human	PMID:10386584
Molecular Function	GO:0042802	identical protein binding	GMEB1	IPI	UniProtKB:Q9Y692	Human	PMID:10386584
Molecular Function	GO:0005515	protein binding	GMEB1	IPI	UniProtKB:Q13114	Human	PMID:32514408
Molecular Function	GO:0005515	protein binding	Gmeb1	IPI	PR:P15919	Mouse	PMID:19324890
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	GMEB1	IDA		Human	PMID:10386584
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Gmeb1	IDA		Mouse	MGI:MGI:1934160|PMID:10692587
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	GMEB1	IDA		Human	PMID:28473536
Cellular Component	GO:0005654	nucleoplasm	GMEB1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	GMEB1	IDA		Human	PMID:10386584
Cellular Component	GO:0005634	nucleus	Gmeb1	IDA		Mouse	PMID:10692587
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Gmeb1	IDA		Mouse	MGI:MGI:1934160|PMID:10692587

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern