Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GJD2
  • Mouse genes Gjd2
  • Rat genes Gjd2
  • Zfish genes gjd2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gjd2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0055077	gap junction hemi-channel activity	gjd2b	IDA		Zfish	PMID:15282192
Molecular Function	GO:0005515	protein binding	Gjd2	IPI	PR:Q9Z0U1	Mouse	PMID:16650609
Molecular Function	GO:0005244	voltage-gated monoatomic ion channel activity	gjd2b	IDA		Zfish	PMID:15282192
Cellular Component	GO:0005922	connexin complex	gjd2b	IDA		Zfish	PMID:15282192
Cellular Component	GO:0005921	gap junction	Gjd2	IDA		Rat	PMID:16650609|RGD:8553398
Cellular Component	GO:0005921	gap junction	gjd2b	IDA		Zfish	PMID:15282192
Biological Process	GO:0007267	cell-cell signaling	Gjd2	IMP	MGI:MGI:2388389	Mouse	PMID:15659592
Biological Process	GO:0007267	cell-cell signaling	Gjd2	IEP		Rat	PMID:12064624|RGD:728473
Biological Process	GO:0007267	cell-cell signaling	gjd2b	IDA		Zfish	PMID:15282192
Biological Process	GO:0007268	chemical synaptic transmission	Gjd2	IMP	MGI:MGI:2388389	Mouse	PMID:15659592
Biological Process	GO:0034220	monoatomic ion transmembrane transport	gjd2b	IDA		Zfish	PMID:15282192|ZFIN:ZDB-PUB-040804-5
Biological Process	GO:0019228	neuronal action potential	Gjd2	IMP	MGI:MGI:2388383	Mouse	PMID:15608630
Biological Process	GO:0007601	visual perception	Gjd2	IMP	MGI:MGI:2388389	Mouse	PMID:15659592

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern