Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GJC2
  • Mouse genes Gjc2
  • Rat genes Gjc2
  • Zfish genes gjc2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gjc2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005243	gap junction channel activity	Gjc2	IDA		Mouse	PMID:11160382
Molecular Function	GO:1903763	gap junction channel activity involved in cell communication by electrical coupling	GJC2	IMP		Human	PMID:17344063
Cellular Component	GO:0005921	gap junction	GJC2	IMP		Human	PMID:17344063
Cellular Component	GO:0005921	gap junction	Gjc2	IDA		Mouse	PMID:11160382
Cellular Component	GO:0005921	gap junction	Gjc2	IDA		Rat	PMID:16203097|RGD:13208516
Cellular Component	GO:0043209	myelin sheath	Gjc2	IDA		Mouse	PMID:20578039
Cellular Component	GO:0043025	neuronal cell body	Gjc2	IDA		Rat	PMID:16203097|RGD:13208516
Cellular Component	GO:0033270	paranode region of axon	Gjc2	IDA		Rat	PMID:16203097|RGD:13208516
Cellular Component	GO:0043204	perikaryon	Gjc2	IDA		Rat	PMID:15293232|RGD:13208522
Cellular Component	GO:1990769	proximal neuron projection	Gjc2	IDA		Rat	PMID:15293232|RGD:13208522
Biological Process	GO:0007420	brain development	Gjc2	IEP		Rat	PMID:14622215|RGD:1299355
Biological Process	GO:0010644	cell communication by electrical coupling	GJC2	IMP		Human	PMID:17344063
Biological Process	GO:0007267	cell-cell signaling	Gjc2	IDA		Mouse	PMID:11160382
Biological Process	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	Gjc2	IMP		Rat	PMID:28278052|RGD:13208599
Biological Process	GO:1904427	positive regulation of calcium ion transmembrane transport	Gjc2	IMP		Rat	PMID:28278052|RGD:13208599
Biological Process	GO:0010628	positive regulation of gene expression	Gjc2	IMP		Rat	PMID:28278052|RGD:13208599
Biological Process	GO:0070447	positive regulation of oligodendrocyte progenitor proliferation	Gjc2	IMP		Rat	PMID:28278052|RGD:13208599
Biological Process	GO:0001932	regulation of protein phosphorylation	Gjc2	IMP		Rat	PMID:28278052|RGD:13208599
Biological Process	GO:0009636	response to toxic substance	Gjc2	IDA		Mouse	PMID:20578039

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern