Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GJB4
  • Mouse genes Gjb4
  • Rat genes Gjb4
  • Zfish genes gjb10,gjb9a,gjb9b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gjb4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005243	gap junction channel activity	Gjb4	IDA		Mouse	MGI:MGI:3603482|PMID:15692151
Molecular Function	GO:0005515	protein binding	GJB4	IPI	UniProtKB:A2RU14	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB4	IPI	UniProtKB:P17152	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB4	IPI	UniProtKB:P21964	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB4	IPI	UniProtKB:P26715	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB4	IPI	UniProtKB:P48230	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB4	IPI	UniProtKB:P55061	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB4	IPI	UniProtKB:Q8N2M4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB4	IPI	UniProtKB:Q8TAF8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GJB4	IPI	UniProtKB:Q8WVX3-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Gjb4	IPI	UniProtKB:Q00977	Mouse	MGI:MGI:3603482|PMID:15692151
Cellular Component	GO:0030054	cell junction	GJB4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005922	connexin complex	Gjb4	IDA		Mouse	MGI:MGI:3603482|PMID:15692151
Cellular Component	GO:0005730	nucleolus	GJB4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	GJB4	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Gjb4	IDA		Mouse	MGI:MGI:3603482|PMID:15692151
Biological Process	GO:0007267	cell-cell signaling	Gjb4	IDA		Mouse	MGI:MGI:3603482|PMID:15692151
Biological Process	GO:1990349	gap junction-mediated intercellular transport	Gjb4	IDA		Mouse	MGI:MGI:3603482|PMID:15692151
Biological Process	GO:0060047	heart contraction	gjb10	IMP	ZFIN:ZDB-CRISPR-210518-2	Zfish	PMID:33048975
Biological Process	GO:0042048	olfactory behavior	Gjb4	IMP	MGI:MGI:3811558	Mouse	PMID:17728008
Biological Process	GO:0007608	sensory perception of smell	Gjb4	IMP	MGI:MGI:3811558	Mouse	PMID:17728008

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern