Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GFUS
  • Mouse genes Gfus
  • Rat genes Gfus
  • Zfish genes gfus.1,gfus.2,gfus.3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gfus

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0050577	GDP-L-fucose synthase activity	GFUS	IDA		Human	PMID:8910301
Molecular Function	GO:0050577	GDP-L-fucose synthase activity	GFUS	IDA		Human	PMID:9525924
Molecular Function	GO:0047918	GDP-mannose 3,5-epimerase activity	GFUS	IDA		Human	PMID:8910301
Molecular Function	GO:0042802	identical protein binding	GFUS	IPI	UniProtKB:Q13630	Human	PMID:23774504
Molecular Function	GO:0042802	identical protein binding	GFUS	IPI	UniProtKB:Q13630	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	GFUS	IPI	UniProtKB:Q5SYC1	Human	PMID:32296183
Cellular Component	GO:0070062	extracellular exosome	GFUS	HDA		Human	PMID:19056867
Biological Process	GO:0042351	'de novo' GDP-L-fucose biosynthetic process	GFUS	IDA		Human	PMID:9525924
Biological Process	GO:0019673	GDP-mannose metabolic process	GFUS	IDA		Human	PMID:9525924
Biological Process	GO:0010595	positive regulation of endothelial cell migration	GFUS	IMP		Human	PMID:18205178
Biological Process	GO:1904906	positive regulation of endothelial cell-matrix adhesion via fibronectin	GFUS	IMP		Human	PMID:18205178
Biological Process	GO:0001913	T cell mediated cytotoxicity	Gfus	IMP		Mouse	PMID:2568889

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern