Tsta3 MGI Mouse Gene Detail - MGI:98857 - tissue specific transplantation antigen P35B

Tsta3 Gene Detail

Symbol

Tsta3
Name

tissue specific transplantation antigen P35B
Synonyms

FX, GDP-fucose synthase, Tstap35b

Feature Type

protein coding gene
IDs

MGI:98857
NCBI Gene: 22122
Gene Overview

MyGene.info: TSTA3

Sequence Map

Chr15:75924684-75929730 bp, - strand
From Ensembl annotation of GRCm38

Mouse Genome Browser
Download
Sequence

5047 bp ± kb flank
Genome Browsers

VEGA | Ensembl | UCSC | NCBI

Genetic Map

Chromosome 15, 35.10 cM
Mapping Data

4 experiments

Human Ortholog

TSTA3, tissue specific transplantation antigen P35B

Vertebrate Orthologs

10

Human Ortholog

TSTA3, tissue specific transplantation antigen P35B
Orthology source: HomoloGene, HGNC
Synonyms

FX, P35B, SDR4E1
Links

HGNC:12390

NCBI Gene ID: 7264

neXtProt AC: NX_Q13630

UniProt: Q13630
Chr Location

8q24.3; chr8:143612618-143618043 (-) GRCh38.p7

HomoloGene

Vertebrate Homology Class 2484
1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;2 zebrafish;1 macaque, rhesus
HCOP

human homology predictions: TSTA3
Gene Tree

Tsta3

less

References

1 with disease annotations

less

Phenotype Summary

19 phenotypes from 1 allele in 1 genetic background
1 images
36 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

14
Chemically induced (other)

3
Gene trapped

5
Radiation induced

2
Targeted

4
Genomic Mutations

5 involving Tsta3
Incidental Mutations

Mutagenetix , APF
Find Mice (IMSR)

16 strains or lines available

Homozygotes for a targeted null mutation frequently die in utero, while survivors are smaller than normal, show colon abnormalities, have reduced fertility, and frequently die before weaning. Heterozygotes also show some embryonic loss.

less

All GO Annotations

15
GO References

4

External Resources

FuncBase

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	receptor	receptor binding	RNA binding	transcription	transferase	transporter

Biological Process

nucleic acid-templated transcription	carbohydrate derivative metabolism	cell death	cell differentiation	cell proliferation	cellular component organization	establishment of localization	homeostatic process	immune system process	lipid metabolic process	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	synapse	vacuole

Click cells to view annotations.

less

cDNA Data

120

Other Mouse Links

Allen Institute

GEO

Expression Atlas

less

Tsta3 interacts with 38 markers (Mir24-1, Mir24-2, Mir29b-2, ...) View All

less

All Sequences

40
RefSeq

16
UniProt

2
CCDS

CCDS27555.1
UniGene

22596

Ensembl

ENSMUSG00000022570 (Evidence)
NCBI Gene

22122

			Length	Strain/Species	Flank
genomic	ENSMUSG00000022570	Ensembl Gene Model \| MGI Sequence Detail	5047	C57BL/6J	± kb
transcript	ENSMUST00000023231	Ensembl \| MGI Sequence Detail	1311	Not Applicable
polypeptide	ENSMUSP00000023231	Ensembl \| MGI Sequence Detail	321	Not Applicable

less

SNPs within 2kb

52 from dbSNP Build 142

less

UniProt

2 Sequences
Protein Ontology

PR:000016776 GDP-L-fucose synthetase

(term hierarchy)
EC

1.1.1.271
InterPro Domains

IPR028614 GDP-L-fucose synthase/GDP-L-colitose synthase

IPR001509 NAD-dependent epimerase/dehydratase

IPR016040 NAD(P)-binding domain

less

All nucleic 121

Genomic 1

cDNA 120

Microarray probesets 3

less

MGD-MRK-15285, MGI:2145965

Summaries

All 64

Diseases 1

Gene Ontology 4

Phenotypes 36
Earliest

J:13437 Bangham JW, Hairy ears, Eh. Mouse News Lett. 1965;33:68
Latest

J:233611 Hirata A, et al., Homeobox family Hoxc localization during murine palate formation. Congenit Anom (Kyoto). 2016 Jul;56(4):172-9

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources Funding Information Warranty Disclaimer & Copyright Notice Send questions and comments to User Support.	last database update 09/12/2017 MGI 6.10