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Tsta3 Gene Detail
Summary
  • Symbol
    Tsta3
  • Name
    tissue specific transplantation antigen P35B
  • Synonyms
    FX, GDP-fucose synthase, Tstap35b
  • Feature Type
    protein coding gene
  • IDs
    MGI:98857
    NCBI Gene: 22122
  • Gene Overview
    MyGene.info: TSTA3
  • Alliance
    gene page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr15:75924669-75929821 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 15, 35.10 cM
  • Mapping Data
    4 experiments
Strain
Comparison
more
  • SNPs within 2kb
    52 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_98857
 protein coding gene Chr15:75924669-75929832 (-)
129S1/SvImJ MGP_129S1SvImJ_G0021966
 protein coding gene Chr15:75974152-75979198 (-)
A/J MGP_AJ_G0021924
 protein coding gene Chr15:73206617-73212323 (-)
AKR/J MGP_AKRJ_G0021907
 protein coding gene Chr15:75185510-75190592 (-)
BALB/cJ MGP_BALBcJ_G0021933
 protein coding gene Chr15:73227967-73233041 (-)
C3H/HeJ MGP_C3HHeJ_G0021705
 protein coding gene Chr15:75246537-75251629 (-)
C57BL/6NJ MGP_C57BL6NJ_G0022373
 protein coding gene Chr15:78810747-78816794 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0019904
 protein coding gene Chr15:69879672-69884727 (-)
CAST/EiJ MGP_CASTEiJ_G0021224
 protein coding gene Chr15:76029503-76034536 (-)
CBA/J MGP_CBAJ_G0021672
 protein coding gene Chr15:81325295-81330440 (-)
DBA/2J MGP_DBA2J_G0021797
 protein coding gene Chr15:72737750-72742796 (-)
FVB/NJ MGP_FVBNJ_G0021778
 protein coding gene Chr15:71788324-71794604 (-)
LP/J MGP_LPJ_G0021868
 protein coding gene Chr15:76055599-76061295 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0021802
 protein coding gene Chr15:86628779-86633950 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0022393
 protein coding gene Chr15:75430031-75435077 (-)
PWK/PhJ MGP_PWKPhJ_G0020965
 protein coding gene Chr15:72874895-72879935 (-)
SPRET/EiJ MGP_SPRETEiJ_G0020804
 protein coding gene Chr15:75159899-75165005 (-)
WSB/EiJ MGP_WSBEiJ_G0021276
 protein coding gene Chr15:75517321-75522367 (-)



Homology
more
  • Human Ortholog
    TSTA3, tissue specific transplantation antigen P35B
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TSTA3, tissue specific transplantation antigen P35B
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FX, P35B, SDR4E1
  • Links
    NCBI Gene ID: 7264
    neXtProt AC: NX_Q13630
    UniProt: Q13630

  • Chr Location
    8q24.3; chr8:143612618-143618043 (-)  GRCh38.p7
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    19 phenotypes from 1 allele in 1 genetic background
    1 images
    36 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Homozygotes for a targeted null mutation frequently die in utero, while survivors are smaller than normal, show colon abnormalities, have reduced fertility, and frequently die before weaning. Heterozygotes also show some embryonic loss.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
    17
  • GO References
    5
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
    121
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 22122 NCBI Gene Model | MGI Sequence Detail 5153 C57BL/6J ±  kb
transcript NM_001357005 RefSeq | MGI Sequence Detail 1334 C57BL/6  
polypeptide P23591 UniProt | EBI | MGI Sequence Detail 321 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 122
    Genomic 1
    cDNA 121

    Microarray probesets 3
Other
Accession IDs
less
MGD-MRK-15285, MGI:2145965
References
more
  • Summaries
    All 66
    Diseases 1
    Gene Ontology 5
    Phenotypes 36
  • Earliest
    J:109968 Roderick TH, et al., Nineteen paracentric chromosomal inversions in mice. Genetics. 1974 Jan;76(1):109-17
  • Latest
    J:233611 Hirata A, et al., Homeobox family Hoxc localization during murine palate formation. Congenit Anom (Kyoto). 2016 Jul;56(4):172-9
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/03/2019
MGI 6.14 		The Jackson Laboratory