Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GBX2
  • Mouse genes Gbx2
  • Rat genes Gbx2
  • Zfish genes gbx2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gbx2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Gbx2	IDA		Mouse	MGI:MGI:5478665|PMID:23144817
Molecular Function	GO:0000981	DNA-binding transcription factor activity, RNA polymerase II-specific	gbx2	IDA		Zfish	PMID:28756106
Molecular Function	GO:0000979	RNA polymerase II core promoter sequence-specific DNA binding	Gbx2	IDA		Mouse	PMID:23144817
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Gbx2	IDA		Mouse	PMID:23144817
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	Gbx2	IDA		Mouse	PMID:23144817
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	GBX2	IDA		Human	PMID:28473536
Cellular Component	GO:0005634	nucleus	Gbx2	IDA		Mouse	PMID:23144817
Biological Process	GO:0048483	autonomic nervous system development	Gbx2	IMP	MGI:MGI:1857634	Mouse	PMID:15996652
Biological Process	GO:0007411	axon guidance	Gbx2	IMP	MGI:MGI:1857634	Mouse	PMID:11967891
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	Gbx2	IGI	MGI:MGI:99604	Mouse	PMID:15996652
Biological Process	GO:0001569	branching involved in blood vessel morphogenesis	Gbx2	IMP	MGI:MGI:1857634	Mouse	PMID:15996652
Biological Process	GO:0021930	cerebellar granule cell precursor proliferation	Gbx2	IMP	MGI:MGI:1857634	Mouse	PMID:16651541
Biological Process	GO:0021549	cerebellum development	Gbx2	IMP	MGI:MGI:1857634	Mouse	PMID:16651541
Biological Process	GO:0021549	cerebellum development	gbx2	IGI	ZFIN:ZDB-GENO-140305-1	Zfish	PMID:24183937
Biological Process	GO:0021549	cerebellum development	gbx2	IGI	ZFIN:ZDB-GENO-140305-1,ZFIN:ZDB-MRPHLNO-060620-3,ZFIN:ZDB-MRPHLNO-060620-5	Zfish	PMID:24183937
Biological Process	GO:0021884	forebrain neuron development	Gbx2	IMP	MGI:MGI:1857634	Mouse	PMID:21048141
Biological Process	GO:0030902	hindbrain development	Gbx2	IMP	MGI:MGI:1857634	Mouse	PMID:15829521
Biological Process	GO:0030902	hindbrain development	Gbx2	IMP	MGI:MGI:1857634	Mouse	PMID:16651541
Biological Process	GO:0030902	hindbrain development	gbx2	IMP	ZFIN:ZDB-MRPHLNO-110324-1	Zfish	PMID:21360792
Biological Process	GO:0042472	inner ear morphogenesis	Gbx2	IMP	MGI:MGI:1857634	Mouse	PMID:15996652
Biological Process	GO:0042472	inner ear morphogenesis	Gbx2	IMP	MGI:MGI:1857634	Mouse	PMID:15829521
Biological Process	GO:0050935	iridophore differentiation	gbx2	IMP	ZFIN:ZDB-MRPHLNO-110324-1	Zfish	PMID:29787751
Biological Process	GO:0030917	midbrain-hindbrain boundary development	Gbx2	IMP	MGI:MGI:1857634	Mouse	PMID:16651541
Biological Process	GO:0021555	midbrain-hindbrain boundary morphogenesis	Gbx2	IMP	MGI:MGI:1857634	Mouse	PMID:16651541
Biological Process	GO:0001755	neural crest cell migration	Gbx2	IMP	MGI:MGI:1857634	Mouse	PMID:15996652
Biological Process	GO:0001755	neural crest cell migration	Gbx2	IMP		Mouse	PMID:23144817
Biological Process	GO:0001755	neural crest cell migration	Gbx2	IMP	MGI:MGI:1857634	Mouse	PMID:19700621
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Gbx2	IDA		Mouse	PMID:23144817
Biological Process	GO:0021568	rhombomere 2 development	Gbx2	IMP	MGI:MGI:1857634	Mouse	PMID:16651541
Biological Process	GO:0021978	telencephalon regionalization	gbx2	IMP	ZFIN:ZDB-GENO-181101-5	Zfish	PMID:29289755
Biological Process	GO:0021794	thalamus development	Gbx2	IMP	MGI:MGI:1857634,MGI:MGI:3840448	Mouse	PMID:19279136
Biological Process	GO:0035239	tube morphogenesis	Gbx2	IMP	MGI:MGI:1857634	Mouse	PMID:15996652

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern