Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GABRA6
  • Mouse genes Gabra6
  • Rat genes Gabra6
  • Zfish genes gabra6a,gabra6b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gabra6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008503	benzodiazepine receptor activity	Gabra6	IMP		Rat	PMID:16554486|RGD:1626493
Molecular Function	GO:0050809	diazepam binding	Gabra6	IDA		Rat	PMID:2166916|RGD:61594
Molecular Function	GO:0004890	GABA-A receptor activity	Gabra6	IDA		Rat	PMID:17395622|RGD:1626515
Molecular Function	GO:0022851	GABA-gated chloride ion channel activity	Gabra6	IMP		Rat	PMID:17395622|RGD:1626515
Molecular Function	GO:1901363	heterocyclic compound binding	Gabra6	IDA		Rat	PMID:2166916|RGD:61594
Molecular Function	GO:0005237	inhibitory extracellular ligand-gated monoatomic ion channel activity	Gabra6	IMP		Rat	PMID:16554486|RGD:1626493
Molecular Function	GO:0044877	protein-containing complex binding	Gabra6	IPI	RGD:61855|RGD:2650|RGD:2651|RGD:61901	Rat	PMID:14713300|RGD:1626497
Molecular Function	GO:0044877	protein-containing complex binding	Gabra6	IPI	RGD:61855|RGD:2650|RGD:2651|RGD:61966	Rat	PMID:14713300|RGD:1626497
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Gabra6	IDA		Mouse	PMID:26134650
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Gabra6	EXP		Mouse	PMID:26134650
Cellular Component	GO:0099192	cerebellar Golgi cell to granule cell synapse	Gabra6	IDA		Mouse	PMID:26134650
Cellular Component	GO:0099192	cerebellar Golgi cell to granule cell synapse	Gabra6	EXP		Mouse	PMID:26134650
Cellular Component	GO:0099192	cerebellar Golgi cell to granule cell synapse	Gabra6	IDA		Rat	PMID:8613776|RGD:1626602
Cellular Component	GO:0030425	dendrite	Gabra6	IDA		Rat	PMID:8613776|RGD:1626602
Cellular Component	GO:0098982	GABA-ergic synapse	Gabra6	IDA		Rat	PMID:8613776|RGD:1626602
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	Gabra6	IDA		Rat	PMID:8613776|RGD:1626602
Cellular Component	GO:0016020	membrane	Gabra6	IDA		Rat	PMID:14713300|RGD:1626497
Cellular Component	GO:0016020	membrane	Gabra6	IDA		Rat	PMID:2166916|RGD:61594
Cellular Component	GO:0032809	neuronal cell body membrane	Gabra6	IDA		Rat	PMID:8613776|RGD:1626602
Cellular Component	GO:0005886	plasma membrane	Gabra6	IDA		Rat	PMID:8613776|RGD:1626602
Cellular Component	GO:0045211	postsynaptic membrane	Gabra6	IDA		Rat	PMID:8613776|RGD:1626602
Cellular Component	GO:0099634	postsynaptic specialization membrane	Gabra6	IDA		Rat	PMID:8613776|RGD:1626602
Cellular Component	GO:0042734	presynaptic membrane	Gabra6	IDA		Rat	PMID:17303643|RGD:1626517
Cellular Component	GO:0043235	receptor complex	Gabra6	IDA		Rat	PMID:14713300|RGD:1626497
Biological Process	GO:0007268	chemical synaptic transmission	Gabra6	EXP		Mouse	MGI:MGI:6201979|PMID:26134650
Biological Process	GO:0099565	chemical synaptic transmission, postsynaptic	Gabra6	EXP		Mouse	MGI:MGI:6201979|PMID:26134650
Biological Process	GO:0034220	monoatomic ion transmembrane transport	Gabra6	EXP		Mouse	MGI:MGI:6201979|PMID:26134650
Biological Process	GO:0060078	regulation of postsynaptic membrane potential	Gabra6	EXP		Mouse	MGI:MGI:6201979|PMID:26134650
Biological Process	GO:0051932	synaptic transmission, GABAergic	Gabra6	IMP		Rat	PMID:16554486|RGD:1626493

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern