Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GABRA3
  • Mouse genes Gabra3
  • Rat genes Gabra3
  • Zfish genes gabra3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gabra3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004890	GABA-A receptor activity	Gabra3	IDA		Rat	PMID:2153588|RGD:61593
Molecular Function	GO:0022851	GABA-gated chloride ion channel activity	GABRA3	IMP		Human	PMID:29053855
Molecular Function	GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	Gabra3	IDA		Rat	PMID:22539847|RGD:13702433
Molecular Function	GO:0099507	ligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	Gabra3	IMP		Rat	PMID:22539847|RGD:13702433
Molecular Function	GO:0005515	protein binding	GABRA3	IPI	UniProtKB:Q9NQX3	Human	PMID:26613940
Molecular Function	GO:0005515	protein binding	Gabra3	IPI	UniProtKB:Q03555-6	Rat	PMID:21880742|RGD:8553839
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Gabra3	EXP		Mouse	PMID:22666188
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Gabra3	IDA		Mouse	PMID:22666188
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Gabra3	EXP		Rat	PMID:22539847|RGD:13702433
Molecular Function	GO:1904315	transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential	Gabra3	IDA		Rat	PMID:22539847|RGD:13702433
Cellular Component	GO:0098982	GABA-ergic synapse	Gabra3	IDA		Mouse	PMID:22666188
Cellular Component	GO:0098982	GABA-ergic synapse	Gabra3	EXP		Mouse	PMID:22666188
Cellular Component	GO:0098982	GABA-ergic synapse	Gabra3	IDA		Rat	PMID:12732237|RGD:13702456
Cellular Component	GO:0098982	GABA-ergic synapse	Gabra3	EXP		Rat	PMID:22539847|RGD:13702433
Cellular Component	GO:0098982	GABA-ergic synapse	Gabra3	IDA		Rat	PMID:22539847|RGD:13702433
Cellular Component	GO:0099634	postsynaptic specialization membrane	Gabra3	IDA		Mouse	PMID:22666188
Cellular Component	GO:0099634	postsynaptic specialization membrane	Gabra3	IDA		Rat	PMID:12732237|RGD:13702456
Cellular Component	GO:0048787	presynaptic active zone membrane	Gabra3	IDA		Rat	PMID:12732237|RGD:13702456
Cellular Component	GO:0045202	synapse	Gabra3	IDA		Rat	PMID:22539847|RGD:13702433
Biological Process	GO:0007268	chemical synaptic transmission	Gabra3	IMP		Rat	PMID:12433958|RGD:1298923

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern