Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes GAA
  • Mouse genes Gaa
  • Rat genes Gaa
  • Zfish genes gaa,gaa2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Gaa

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0004558	alpha-1,4-glucosidase activity	GAA	IDA		Human	PMID:29061980
Molecular Function	GO:0004558	alpha-1,4-glucosidase activity	GAA	IDA		Human	PMID:9505277
Molecular Function	GO:0004558	alpha-1,4-glucosidase activity	Gaa	IMP	MGI:MGI:2179961	Mouse	PMID:9384603
Molecular Function	GO:0004558	alpha-1,4-glucosidase activity	Gaa	IMP	MGI:MGI:2148550	Mouse	PMID:9668092
Molecular Function	GO:0004558	alpha-1,4-glucosidase activity	Gaa	IMP	MGI:MGI:2148550	Mouse	PMID:11590121
Molecular Function	GO:0004558	alpha-1,4-glucosidase activity	Gaa	IDA		Mouse	PMID:7323947
Molecular Function	GO:0004558	alpha-1,4-glucosidase activity	Gaa	IMP	MGI:MGI:2179961	Mouse	PMID:11328962
Molecular Function	GO:0004558	alpha-1,4-glucosidase activity	Gaa	IMP	MGI:MGI:2148550	Mouse	PMID:11785984
Molecular Function	GO:0004558	alpha-1,4-glucosidase activity	Gaa	IMP	MGI:MGI:2148550	Mouse	PMID:15169761
Molecular Function	GO:0004558	alpha-1,4-glucosidase activity	Gaa	IMP		Rat	PMID:2193931|RGD:1599504
Molecular Function	GO:0004558	alpha-1,4-glucosidase activity	Gaa	IDA		Rat	PMID:8702598|RGD:1625498
Molecular Function	GO:0004558	alpha-1,4-glucosidase activity	Gaa	IDA		Rat	PMID:8710802|RGD:1599506
Molecular Function	GO:0090599	alpha-glucosidase activity	GAA	EXP		Human	PMID:5264799
Molecular Function	GO:0090599	alpha-glucosidase activity	gaa	IDA		Zfish	PMID:28045567
Molecular Function	GO:0030246	carbohydrate binding	Gaa	IDA		Rat	PMID:8702598|RGD:1625498
Cellular Component	GO:0120282	autolysosome lumen	Gaa	IMP	MGI:MGI:2148550	Mouse	PMID:9668092
Cellular Component	GO:0070062	extracellular exosome	GAA	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	GAA	HDA		Human	PMID:23533145
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	GAA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005765	lysosomal membrane	GAA	HDA		Human	PMID:17897319
Cellular Component	GO:0005764	lysosome	GAA	IDA		Human	PMID:9505277
Cellular Component	GO:0005764	lysosome	Gaa	IMP	MGI:MGI:2179961	Mouse	PMID:15207257
Cellular Component	GO:0005764	lysosome	Gaa	IDA		Rat	PMID:2193931|RGD:1599504
Cellular Component	GO:0005764	lysosome	Gaa	IDA		Rat	PMID:8702598|RGD:1625498
Cellular Component	GO:0005764	lysosome	Gaa	IDA		Rat	PMID:8710802|RGD:1599506
Cellular Component	GO:0016020	membrane	GAA	HDA		Human	PMID:19946888
Cellular Component	GO:0016020	membrane	Gaa	IMP		Mouse	MGI:MGI:4420830|PMID:20080761
Biological Process	GO:0035904	aorta development	Gaa	IMP	MGI:MGI:2179955	Mouse	PMID:32428018
Biological Process	GO:0060048	cardiac muscle contraction	GAA	IMP		Human	PMID:10931430
Biological Process	GO:0002086	diaphragm contraction	GAA	IMP		Human	PMID:16917947
Biological Process	GO:0002086	diaphragm contraction	Gaa	IMP	MGI:MGI:2148550	Mouse	PMID:15169761
Biological Process	GO:0005980	glycogen catabolic process	GAA	IDA		Human	PMID:29061980
Biological Process	GO:0005980	glycogen catabolic process	GAA	IDA		Human	PMID:9505277
Biological Process	GO:0005980	glycogen catabolic process	Gaa	IMP	MGI:MGI:2148550	Mouse	PMID:11785984
Biological Process	GO:0005980	glycogen catabolic process	Gaa	IMP	MGI:MGI:2179955	Mouse	PMID:10838256
Biological Process	GO:0005980	glycogen catabolic process	Gaa	IMP	MGI:MGI:2179961	Mouse	PMID:11328962
Biological Process	GO:0005980	glycogen catabolic process	Gaa	IMP	MGI:MGI:2179960	Mouse	PMID:10838256
Biological Process	GO:0005980	glycogen catabolic process	Gaa	IMP		Rat	PMID:2193931|RGD:1599504
Biological Process	GO:0005980	glycogen catabolic process	Gaa	IDA		Rat	PMID:8710802|RGD:1599506
Biological Process	GO:0005980	glycogen catabolic process	gaa	IMP	ZFIN:ZDB-FISH-210310-1	Zfish	PMID:31917327
Biological Process	GO:0005980	glycogen catabolic process	gaa	IMP	ZFIN:ZDB-FISH-210310-2	Zfish	PMID:31917327
Biological Process	GO:0005977	glycogen metabolic process	Gaa	IMP	MGI:MGI:2148550	Mouse	PMID:9668092
Biological Process	GO:0005977	glycogen metabolic process	Gaa	IMP	MGI:MGI:2179961	Mouse	PMID:15207257
Biological Process	GO:0005977	glycogen metabolic process	Gaa	IMP	MGI:MGI:2179961	Mouse	PMID:12115977
Biological Process	GO:0005977	glycogen metabolic process	Gaa	IMP	MGI:MGI:2179961	Mouse	PMID:10547605
Biological Process	GO:0005977	glycogen metabolic process	Gaa	IMP	MGI:MGI:2148550	Mouse	PMID:15169761
Biological Process	GO:0005977	glycogen metabolic process	Gaa	IMP	MGI:MGI:2148550	Mouse	PMID:11590121
Biological Process	GO:0005977	glycogen metabolic process	Gaa	IMP	MGI:MGI:2179961	Mouse	PMID:9384603
Biological Process	GO:0061723	glycophagy	Gaa	IMP	MGI:MGI:2148550	Mouse	PMID:12739885
Biological Process	GO:0003007	heart morphogenesis	Gaa	IMP	MGI:MGI:2179961	Mouse	PMID:9384603
Biological Process	GO:0007626	locomotory behavior	Gaa	IMP	MGI:MGI:2179961	Mouse	PMID:10547605
Biological Process	GO:0007626	locomotory behavior	Gaa	IMP	MGI:MGI:2148550	Mouse	PMID:10838256
Biological Process	GO:0007626	locomotory behavior	Gaa	IMP	MGI:MGI:2148550	Mouse	PMID:9668092
Biological Process	GO:0007040	lysosome organization	GAA	IMP		Human	PMID:7717400
Biological Process	GO:0007040	lysosome organization	Gaa	IMP	MGI:MGI:2179961	Mouse	PMID:11328962
Biological Process	GO:0007040	lysosome organization	Gaa	IMP	MGI:MGI:2148550	Mouse	PMID:9668092
Biological Process	GO:0007040	lysosome organization	Gaa	IMP	MGI:MGI:2148550	Mouse	PMID:15169761
Biological Process	GO:0007040	lysosome organization	Gaa	IMP	MGI:MGI:2179961	Mouse	PMID:10547605
Biological Process	GO:0007040	lysosome organization	Gaa	IMP	MGI:MGI:2179961	Mouse	PMID:9384603
Biological Process	GO:0007040	lysosome organization	Gaa	IMP	MGI:MGI:2179961	Mouse	PMID:12115977
Biological Process	GO:0046716	muscle cell cellular homeostasis	Gaa	IMP	MGI:MGI:2179961	Mouse	PMID:15674828
Biological Process	GO:0046716	muscle cell cellular homeostasis	Gaa	IMP	MGI:MGI:2179961	Mouse	PMID:10547605
Biological Process	GO:0046716	muscle cell cellular homeostasis	Gaa	IMP	MGI:MGI:2179961	Mouse	PMID:12115977
Biological Process	GO:0046716	muscle cell cellular homeostasis	Gaa	IMP	MGI:MGI:2148550	Mouse	PMID:9668092
Biological Process	GO:0046716	muscle cell cellular homeostasis	Gaa	IMP	MGI:MGI:2148550	Mouse	PMID:10838256
Biological Process	GO:0050885	neuromuscular process controlling balance	Gaa	IMP	MGI:MGI:2148550	Mouse	PMID:10838256
Biological Process	GO:0050884	neuromuscular process controlling posture	Gaa	IMP	MGI:MGI:2179961	Mouse	PMID:10547605
Biological Process	GO:0007274	neuromuscular synaptic transmission	gaa	IMP	ZFIN:ZDB-MRPHLNO-200918-2	Zfish	PMID:33724918
Biological Process	GO:0002026	regulation of the force of heart contraction	Gaa	IMP	MGI:MGI:2179961	Mouse	PMID:11328962
Biological Process	GO:0006941	striated muscle contraction	Gaa	IMP	MGI:MGI:2179961	Mouse	PMID:12115977
Biological Process	GO:0006941	striated muscle contraction	Gaa	IMP	MGI:MGI:2179961	Mouse	PMID:15674828
Biological Process	GO:0007271	synaptic transmission, cholinergic	gaa	IMP	ZFIN:ZDB-MRPHLNO-200918-2	Zfish	PMID:33724918
Biological Process	GO:0009888	tissue development	Gaa	IMP	MGI:MGI:2179961	Mouse	PMID:10547605
Biological Process	GO:0043181	vacuolar sequestering	GAA	IMP		Human	PMID:10931430

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern