Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FZD10
  • Mouse genes Fzd10
  • Rat genes
  • Zfish genes fzd10
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fzd10

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	FZD10	IPI	UniProtKB:Q9Y5L2	Human	PMID:15930302
Molecular Function	GO:0005515	protein binding	FZD10	IPI	UniProtKB:Q99972	Human	PMID:19188438
Molecular Function	GO:0005515	protein binding	FZD10	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FZD10	IPI	UniProtKB:O95273	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FZD10	IPI	UniProtKB:P07237	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FZD10	IPI	UniProtKB:P0DPK4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FZD10	IPI	UniProtKB:P60410	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FZD10	IPI	UniProtKB:Q07627	Human	PMID:32296183
Molecular Function	GO:0042813	Wnt receptor activity	FZD10	IDA		Human	PMID:28733458
Molecular Function	GO:0042813	Wnt receptor activity	fzd10	IMP		Zfish	PMID:12676325
Molecular Function	GO:0017147	Wnt-protein binding	Fzd10	IPI	PR:P28047	Mouse	PMID:15923619
Cellular Component	GO:0009986	cell surface	FZD10	IDA		Human	PMID:18271942
Cellular Component	GO:0005737	cytoplasm	FZD10	IDA		Human	PMID:16007199
Cellular Component	GO:0005654	nucleoplasm	FZD10	IDA		Human	GO_REF:0000052
Biological Process	GO:0060070	canonical Wnt signaling pathway	FZD10	IDA		Human	PMID:28733458
Biological Process	GO:0090504	epiboly	fzd10	IGI	ZFIN:ZDB-MRPHLNO-050923-5,ZFIN:ZDB-MRPHLNO-120203-1,ZFIN:ZDB-MRPHLNO-130219-1	Zfish	PMID:23349976
Biological Process	GO:0034260	negative regulation of GTPase activity	FZD10	IMP		Human	PMID:19137009
Biological Process	GO:0038031	non-canonical Wnt signaling pathway via JNK cascade	FZD10	IMP		Human	PMID:19137009
Biological Process	GO:0043547	positive regulation of GTPase activity	FZD10	IMP		Human	PMID:19137009
Biological Process	GO:0043507	positive regulation of JUN kinase activity	FZD10	IMP		Human	PMID:19137009
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	FZD10	IMP		Human	PMID:19137009
Biological Process	GO:0016055	Wnt signaling pathway	Fzd10	IGI	MGI:MGI:98961	Mouse	PMID:15923619
Biological Process	GO:0016055	Wnt signaling pathway	Fzd10	IGI	MGI:MGI:1196625	Mouse	PMID:15923619
Biological Process	GO:0016055	Wnt signaling pathway	Fzd10	IGI	MGI:MGI:1278315	Mouse	PMID:15923619
Biological Process	GO:0016055	Wnt signaling pathway	fzd10	IMP		Zfish	PMID:12676325

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern