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Fzd10 Gene Detail
Summary
  • Symbol
    Fzd10
  • Name
    frizzled class receptor 10
  • Synonyms
    Fz-10
  • Feature Type
    protein coding gene
  • IDs
    MGI:2136761
    NCBI Gene: 93897
  • Gene Overview
    MyGene.info: FZD10
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:128601106-128604093 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 67.67 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    10 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_2136761
protein coding gene Chr5:128600844-128604093 (.)
129S1/SvImJ MGP_129S1SvImJ_G0030119
protein coding gene Chr5:132628841-132632086 (+)
A/J MGP_AJ_G0030086
protein coding gene Chr5:127055061-127058308 (+)
AKR/J MGP_AKRJ_G0030020
protein coding gene Chr5:131187498-131190747 (+)
BALB/cJ MGP_BALBcJ_G0030096
protein coding gene Chr5:128402655-128405902 (+)
C3H/HeJ MGP_C3HHeJ_G0029813
protein coding gene Chr5:131753638-131756794 (+)
C57BL/6NJ MGP_C57BL6NJ_G0030549
protein coding gene Chr5:137705851-137709088 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027774
protein coding gene Chr5:121479638-121482865 (+)
CAST/EiJ MGP_CASTEiJ_G0029222
protein coding gene Chr5:131000118-131003355 (+)
CBA/J MGP_CBAJ_G0029783
protein coding gene Chr5:143086067-143089314 (+)
DBA/2J MGP_DBA2J_G0029933
protein coding gene Chr5:127046078-127049328 (+)
FVB/NJ MGP_FVBNJ_G0029889
protein coding gene Chr5:126098349-126101595 (+)
LP/J MGP_LPJ_G0030022
protein coding gene Chr5:133142126-133145371 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029920
protein coding gene Chr5:146483214-146486461 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0030590
protein coding gene Chr5:130844795-130848040 (+)
PWK/PhJ MGP_PWKPhJ_G0028936
protein coding gene Chr5:125934758-125937934 (+)
SPRET/EiJ MGP_SPRETEiJ_G0028773
protein coding gene Chr5:128416828-128420065 (+)
WSB/EiJ MGP_WSBEiJ_G0029296
protein coding gene Chr5:131507955-131511201 (+)



Homology
more
  • Human Ortholog
    FZD10, frizzled class receptor 10
  • Vertebrate Orthologs
    10
  • Human Ortholog
    FZD10, frizzled class receptor 10
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CD350, Fz10, FZ-10, FzE7, hFz10
  • Links
    NCBI Gene ID: 11211
    neXtProt AC: NX_Q9ULW2
    UniProt: Q9ULW2

  • Chr Location
    12q24.33; chr12:130162459-130165740 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
Homozygous mutation of this gene does not appear to result in a phenotype.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 93897 NCBI Gene Model | MGI Sequence Detail 2988 C57BL/6J ±  kb
transcript NM_175284 RefSeq | MGI Sequence Detail 3005 CD-1  
polypeptide Q8BKG4 UniProt | EBI | MGI Sequence Detail 582 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 26
    cDNA 16
    Primer pair 9
    Other 1

    Microarray probesets 3
References
more
  • Summaries
    All 71
    Developmental Gene Expression 41
    Gene Ontology 6
    Phenotypes 7
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:261380 Concepcion D, et al., Tbx6 controls left-right asymmetry through regulation of Gdf1. Biol Open. 2018 May 4;7(5)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory