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Fzd10
Gene Detail
 Symbol
Name
ID
Fzd10
frizzled homolog 10 (Drosophila)
MGI:2136761
Synonyms Fz-10
Feature Type protein coding gene
Genetic Map
Chromosome 5
67.67 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr5:128600844-128604093 bp, + strand
From VEGA annotation of GRCm38

  3250 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:21411  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: G protein-coupled receptor frizzled
Gene Tree: Fzd10

Human
homologs
Human Homolog FZD10, frizzled class receptor 10
NCBI Gene ID 11211
neXtProt AC  NX_Q9ULW2
Human Synonyms  CD350, Fz10, FZ-10, FzE7, hFz10
Human Chr (Location)  12q24.33; chr12:130162459-130165740 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutation of this gene does not appear to result in a phenotype.
 
Interactions
Fzd10 interacts with 229 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (30 annotations)
Process brain development, canonical Wnt signaling pathway, ...
Component cell projection, cell surface, ...
Function G-protein coupled receptor activity, PDZ domain binding, ...
This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase
Expression
Literature Summary: (31 records)
Data Summary: Results (425)    Tissues (289)    Images (111)
Theiler Stages: 1, 2, 3, 4, 5, 7, 8, 9, 10, 11, 13, 14, 15, 17, 19, 20, 22, 23, 24, 25, 28
Assay TypeResults
RNA in situ 267
In situ reporter (knock in) 60
RT-PCR 98
cDNA source data(13)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(21) cDNA(13) Primer pair(8)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000027707 (Evidence)
Ensembl Gene ModelENSMUSG00000081683 (Evidence)
Entrez Gene93897 (Evidence)
UniGene197628
DFCITC1586435
DoTSDT.101260357
NIA Mouse Gene IndexU006219
Consensus CDS ProjectCCDS51652.1
International Mouse Knockout Project StatusFzd10
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027707 VEGA Gene Model | MGI Sequence Detail 3250 C57BL/6J ±  kb
transcript OTTMUST00000068559 VEGA | MGI Sequence Detail 3250 Not Applicable 
polypeptide OTTMUSP00000034695 VEGA | MGI Sequence Detail 582 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(2) UniProt(3)
Polymorphisms SNPs within 2kb(13 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026549 Frizzled-10
InterPro IPR020067 Frizzled domain
InterPro IPR000539 Frizzled protein
InterPro IPR015526 Frizzled/secreted frizzled-related protein
InterPro IPR017981 GPCR, family 2-like
Protein Ontology PR:000001453 frizzled-10
References (Earliest) J:69787 Kim AS, et al., Wnt receptors and Wnt inhibitors are expressed in gradients in the developing telencephalon. Mech Dev. 2001 May;103(1-2):167-72
(Latest) J:207050 Zhao X, et al., Dynamic expression of secreted Frizzled-related protein 3 (sFRP3) in the developing mouse spinal cord and dorsal root ganglia. Neuroscience. 2013 Jul 1;248C:594-601
All references(56)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/23/2014
MGI 5.19
The Jackson Laboratory