Fzd10
Gene Detail

Symbol Name ID

Fzd10 frizzled homolog 10 (Drosophila) MGI:2136761

Synonyms

Fz-10

Feature Type

protein coding gene

Genetic Map

Chromosome 5

67.67 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr5:128600844-128604093 bp, + strand From VEGA annotation of GRCm38   3250 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Mammalian homology

human; cattle; chimpanzee; dog, domestic    (Mammalian Orthology)
Comparative Map (Mouse/Human Fzd10 ± 2 cM)

Protein SuperFamily: G protein-coupled receptor frizzled
Gene Tree: Fzd10

Human ortholog

FZD10 frizzled family receptor 10 NCBI Gene ID 11211
Human Synonyms: CD350, Fz10, FZ-10, FzE7, hFz10
Human Chr12:130647032-130650285 bp, + strand Reference GRCh37.p2 Primary Assembly

Alleles and phenotypes

All alleles(1) : Targeted(1)
 

Homozygous mutation of this gene does not appear to result in a phenotype.

 

Gene Ontology (GO) classifications

All GO classifications: (30 annotations)

Process	brain development, canonical Wnt receptor signaling pathway, ...
Component	cell projection, cell surface, ...
Function	G-protein coupled receptor activity, PDZ domain binding, ...

This is a GO Consortium Reference Genome Project gene.
External Resources: FuncBase

Expression

Literature Summary: (27 records)
Data Summary: Results (410)    Tissues (279)    Images (103)
Theiler Stages: 1, 2, 3, 4, 5, 13, 15, 17, 19, 20, 22, 23, 24, 25, 28

Assay Type	Results
RNA in situ	257
In situ reporter (knock in)	60
RT-PCR	93

cDNA source data(13)
External Resources: Allen Institute   GENSAT   GEO   ArrayExpress

Molecular reagents

All nucleic(20) cDNA(13) Primer pair(7)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000027707 (Evidence)
Ensembl Gene Model	ENSMUSG00000081683 (Evidence)
Entrez Gene	93897 (Evidence)
UniGene	197628
DFCI	TC1586435
DoTS	DT.101260357
NIA Mouse Gene Index	U006219
Consensus CDS Project	CCDS51652.1
International Mouse Knockout Project Status	Fzd10

Sequences

Length	Strain/Species
genomic	OTTMUSG00000027707	VEGA Gene Model | MGI Sequence Detail	3250	C57BL/6J
transcript	OTTMUST00000068559	VEGA | MGI Sequence Detail	3250	Not Applicable
polypeptide	OTTMUSP00000034695	VEGA | MGI Sequence Detail	582	Not Applicable

All sequences(22) RefSeq(2) UniProt(3)

Polymorphisms

SNPs(5 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR026549	Frizzled-10
InterPro	IPR020067	Frizzled domain
InterPro	IPR000539	Frizzled protein
InterPro	IPR015526	Frizzled/secreted frizzled-related protein
InterPro	IPR017981	GPCR, family 2-like
Protein Ontology	PR:000001453	frizzled-10

References

(Earliest) J:69787 Kim AS, et al., Wnt receptors and Wnt inhibitors are expressed in gradients in the developing telencephalon. Mech Dev. 2001 May;103(1-2):167-72
(Latest) J:182256 Gu X, et al., Inducible genetic lineage tracing of cortical hem derived Cajal-Retzius cells reveals novel properties. PLoS One. 2011;6(12):e28653
All references(52)