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Fzd10
Gene Detail
Symbol

Name
ID
Fzd10
frizzled homolog 10 (Drosophila)
MGI:2136761
Synonyms
Fz-10
Feature Type
protein coding gene
Genetic Map
Chromosome 5
67.67 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr5:128600844-128604093 bp, + strand
From VEGA annotation of GRCm38

  3250 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:21411  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: FZD10
Protein SuperFamily: G protein-coupled receptor frizzled
Gene Tree: Fzd10

Human
homologs
FZD10, frizzled class receptor 10
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 11211
neXtProt AC: NX_Q9ULW2

Human Synonyms: CD350, Fz10, FZ-10, FzE7, hFz10

Human Chr (Location): 12q24.33; chr12:130162459-130165740 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Homozygous mutation of this gene does not appear to result in a phenotype.
 
Interactions
Fzd10 interacts with 229 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
Expression
Literature Summary: (34 records)
Data Summary: Results (421)    Tissues (290)    Images (111)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 267
In situ reporter (knock in) 60
RT-PCR 94
cDNA source data(13)
Other mouse links: Allen Institute   GENSAT   GEO   Expression Atlas
Other vertebrate links: GEISHA FZD10 ; Xenbase fzd10 ; ZFIN fzd10    NEW 
Molecular
reagents
All nucleic(21) cDNA(13) Primer pair(8)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000027707 (Evidence)
Ensembl Gene Model ENSMUSG00000081683 (Evidence)
Entrez Gene 93897 (Evidence)
UniGene 197628
DFCI TC1586435
DoTS DT.101260357
NIA Mouse Gene Index U006219
Consensus CDS Project CCDS51652.1
International Mouse Phenotyping Consortium Status Fzd10
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000027707 VEGA Gene Model | MGI Sequence Detail 3250 C57BL/6J ±  kb
transcript OTTMUST00000068559 VEGA | MGI Sequence Detail 3250 Not Applicable 
polypeptide OTTMUSP00000034695 VEGA | MGI Sequence Detail 582 Not Applicable 

For the selected sequences
All sequences(22) RefSeq(2) UniProt(3)
Polymorphisms
SNPs within 2kb(13 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR026549 Frizzled-10
InterPro IPR020067 Frizzled domain
InterPro IPR000539 Frizzled protein
InterPro IPR015526 Frizzled/secreted frizzled-related protein
InterPro IPR017981 GPCR, family 2-like
Protein Ontology PR:000001453 frizzled-10
References
(Earliest) J:69787 Kim AS, et al., Wnt receptors and Wnt inhibitors are expressed in gradients in the developing telencephalon. Mech Dev. 2001 May;103(1-2):167-72
(Latest) J:217500 Cui CY, et al., Involvement of Wnt, Eda and Shh at defined stages of sweat gland development. Development. 2014 Oct;141(19):3752-60
All references(58)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
06/30/2015
MGI 5.22
The Jackson Laboratory