Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FOXF1
  • Mouse genes Foxf1
  • Rat genes Foxf1
  • Zfish genes foxf1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Foxf1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	FOXF1	IDA		Human	PMID:9769171
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	FOXF1	IMP		Human	PMID:8626802
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Foxf1	IDA		Mouse	PMID:15987774
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	FOXF1	IMP		Human	PMID:8626802
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Foxf1	IDA		Mouse	PMID:7958446
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Foxf1	IDA		Mouse	PMID:17261592
Cellular Component	GO:0005634	nucleus	Foxf1	IDA		Mouse	PMID:17261592
Biological Process	GO:0009887	animal organ morphogenesis	Foxf1	IMP	MGI:MGI:2179135	Mouse	PMID:11809759
Biological Process	GO:0001568	blood vessel development	FOXF1	IMP		Human	PMID:19500772
Biological Process	GO:0003214	cardiac left ventricle morphogenesis	FOXF1	IMP		Human	PMID:19500772
Biological Process	GO:0098609	cell-cell adhesion	Foxf1	IMP	MGI:MGI:1929432	Mouse	PMID:11124112
Biological Process	GO:0071345	cellular response to cytokine stimulus	Foxf1	IDA		Mouse	PMID:9486531
Biological Process	GO:0071407	cellular response to organic cyclic compound	Foxf1	IMP	MGI:MGI:2179135	Mouse	PMID:18421012
Biological Process	GO:0014822	detection of wounding	Foxf1	IMP	MGI:MGI:2179135	Mouse	PMID:12500195
Biological Process	GO:0007368	determination of left/right symmetry	Foxf1	IMP		Mouse	PMID:11493558
Biological Process	GO:0048565	digestive tract development	FOXF1	IMP		Human	PMID:19500772
Biological Process	GO:0097070	ductus arteriosus closure	FOXF1	IMP		Human	PMID:19500772
Biological Process	GO:0048566	embryonic digestive tract development	Foxf1	IGI	MGI:MGI:1347479	Mouse	PMID:16439479
Biological Process	GO:0048557	embryonic digestive tract morphogenesis	FOXF1	IMP		Human	PMID:19500772
Biological Process	GO:0048613	embryonic ectodermal digestive tract morphogenesis	FOXF1	IMP		Human	PMID:19500772
Biological Process	GO:0048617	embryonic foregut morphogenesis	Foxf1	IMP	MGI:MGI:1929432	Mouse	PMID:11493558
Biological Process	GO:0003197	endocardial cushion development	FOXF1	IMP		Human	PMID:19500772
Biological Process	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development	Foxf1	IGI	MGI:MGI:96432	Mouse	PMID:16691571
Biological Process	GO:0060441	epithelial tube branching involved in lung morphogenesis	Foxf1	IMP	MGI:MGI:1929432	Mouse	PMID:11493558
Biological Process	GO:0045198	establishment of epithelial cell apical/basal polarity	Foxf1	IGI	MGI:MGI:1347479	Mouse	PMID:16439479
Biological Process	GO:0030198	extracellular matrix organization	Foxf1	IGI	MGI:MGI:1347479	Mouse	PMID:16439479
Biological Process	GO:0007507	heart development	FOXF1	IMP		Human	PMID:19500772
Biological Process	GO:0001701	in utero embryonic development	FOXF1	IMP		Human	PMID:19500772
Biological Process	GO:0001701	in utero embryonic development	Foxf1	IMP	MGI:MGI:1929432	Mouse	PMID:11124112
Biological Process	GO:0001701	in utero embryonic development	Foxf1	IMP	MGI:MGI:1929432	Mouse	PMID:11493558
Biological Process	GO:0048371	lateral mesodermal cell differentiation	Foxf1	IMP	MGI:MGI:1929432	Mouse	PMID:11124112
Biological Process	GO:0048286	lung alveolus development	Foxf1	IMP	MGI:MGI:1929432	Mouse	PMID:11493558
Biological Process	GO:0030324	lung development	FOXF1	IMP		Human	PMID:19500772
Biological Process	GO:0030324	lung development	Foxf1	IMP	MGI:MGI:2179135	Mouse	PMID:11437453
Biological Process	GO:0030324	lung development	Foxf1	IMP	MGI:MGI:1929432	Mouse	PMID:11493558
Biological Process	GO:0060463	lung lobe morphogenesis	Foxf1	IMP	MGI:MGI:1929432	Mouse	PMID:11493558
Biological Process	GO:0060425	lung morphogenesis	Foxf1	IMP	MGI:MGI:1929432	Mouse	PMID:11493558
Biological Process	GO:0060426	lung vasculature development	FOXF1	IMP		Human	PMID:19500772
Biological Process	GO:0090131	mesenchyme migration	Foxf1	IMP	MGI:MGI:2179135	Mouse	PMID:17261592
Biological Process	GO:0007498	mesoderm development	Foxf1	IMP	MGI:MGI:1929432	Mouse	PMID:11493558
Biological Process	GO:0007498	mesoderm development	Foxf1	IGI	MGI:MGI:1197522	Mouse	PMID:11124112
Biological Process	GO:0048333	mesodermal cell differentiation	Foxf1	IMP	MGI:MGI:1929432	Mouse	PMID:17881493
Biological Process	GO:0048333	mesodermal cell differentiation	Foxf1	IGI	MGI:MGI:88180	Mouse	PMID:17881493
Biological Process	GO:0007494	midgut development	FOXF1	IMP		Human	PMID:19500772
Biological Process	GO:0001763	morphogenesis of a branching structure	FOXF1	IMP		Human	PMID:19500772
Biological Process	GO:0050728	negative regulation of inflammatory response	Foxf1	IMP	MGI:MGI:2179135	Mouse	PMID:18421012
Biological Process	GO:0043305	negative regulation of mast cell degranulation	Foxf1	IMP	MGI:MGI:2179135	Mouse	PMID:18421012
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Foxf1	IMP	MGI:MGI:1929432	Mouse	PMID:11124112
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Foxf1	IMP	MGI:MGI:2179135	Mouse	PMID:18421012
Biological Process	GO:0031016	pancreas development	FOXF1	IMP		Human	PMID:19500772
Biological Process	GO:0030335	positive regulation of cell migration	Foxf1	IMP	MGI:MGI:2179135	Mouse	PMID:17261592
Biological Process	GO:0010811	positive regulation of cell-substrate adhesion	Foxf1	IMP	MGI:MGI:2179135	Mouse	PMID:17261592
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	FOXF1	IDA		Human	PMID:8626802
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	FOXF1	IDA		Human	PMID:9769171
Biological Process	GO:0002053	positive regulation of mesenchymal cell proliferation	Foxf1	IMP	MGI:MGI:1929432	Mouse	PMID:11124112
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	FOXF1	IMP		Human	PMID:8626802
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Foxf1	IDA		Mouse	PMID:17261592
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Foxf1	IDA		Mouse	PMID:9486531
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Foxf1	IDA		Mouse	PMID:7958446
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Foxf1	IMP	MGI:MGI:2179135	Mouse	PMID:17261592
Biological Process	GO:0030323	respiratory tube development	FOXF1	IMP		Human	PMID:19500772
Biological Process	GO:0060461	right lung morphogenesis	Foxf1	IMP	MGI:MGI:1929432	Mouse	PMID:11493558
Biological Process	GO:0051145	smooth muscle cell differentiation	Foxf1	IMP	MGI:MGI:1929432	Mouse	PMID:17881493
Biological Process	GO:0051145	smooth muscle cell differentiation	Foxf1	IGI	MGI:MGI:88180	Mouse	PMID:17881493
Biological Process	GO:0051145	smooth muscle cell differentiation	Foxf1	IMP	MGI:MGI:1929432	Mouse	PMID:11493558
Biological Process	GO:0007224	smoothened signaling pathway	Foxf1	IDA		Mouse	PMID:11493558
Biological Process	GO:0001756	somitogenesis	Foxf1	IMP	MGI:MGI:1929432	Mouse	PMID:11124112
Biological Process	GO:0002040	sprouting angiogenesis	foxf1	IMP	ZFIN:ZDB-MRPHLNO-181001-2	Zfish	PMID:29963552
Biological Process	GO:0060438	trachea development	FOXF1	IMP		Human	PMID:19500772
Biological Process	GO:0060438	trachea development	Foxf1	IMP	MGI:MGI:1929432	Mouse	PMID:11493558
Biological Process	GO:0072189	ureter development	FOXF1	IMP		Human	PMID:19500772
Biological Process	GO:0001570	vasculogenesis	Foxf1	IMP	MGI:MGI:1929432	Mouse	PMID:17881493
Biological Process	GO:0001570	vasculogenesis	Foxf1	IMP	MGI:MGI:2179135	Mouse	PMID:11437453
Biological Process	GO:0001570	vasculogenesis	Foxf1	IMP	MGI:MGI:1929432	Mouse	PMID:11124112
Biological Process	GO:0060841	venous blood vessel development	FOXF1	IMP		Human	PMID:19500772

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern