Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FOLH1,FOLH1B
  • Mouse genes Folh1
  • Rat genes Folh1
  • Zfish genes naalad2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Folh1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:1904492	Ac-Asp-Glu binding	FOLH1	IDA		Human	PMID:24863754
Molecular Function	GO:0004180	carboxypeptidase activity	Folh1	IDA		Mouse	PMID:21908619
Molecular Function	GO:0016805	dipeptidase activity	Folh1	IDA		Mouse	PMID:21908619
Molecular Function	GO:0004181	metallocarboxypeptidase activity	FOLH1	IDA		Human	PMID:12949938
Molecular Function	GO:0004181	metallocarboxypeptidase activity	FOLH1	IDA		Human	PMID:17241121
Molecular Function	GO:0004181	metallocarboxypeptidase activity	FOLH1	IDA		Human	PMID:24863754
Molecular Function	GO:0004181	metallocarboxypeptidase activity	FOLH1B	IDA		Human	PMID:17241121
Molecular Function	GO:0008233	peptidase activity	Folh1	IDA		Mouse	PMID:11210180
Molecular Function	GO:1904493	tetrahydrofolyl-poly(glutamate) polymer binding	FOLH1	IDA		Human	PMID:24863754
Cellular Component	GO:0009986	cell surface	FOLH1	IDA		Human	PMID:12949938
Cellular Component	GO:0070062	extracellular exosome	FOLH1	HDA		Human	PMID:23533145
Cellular Component	GO:0070062	extracellular exosome	FOLH1B	HDA		Human	PMID:23533145
Cellular Component	GO:0016020	membrane	Folh1	IDA		Mouse	PMID:21908619
Cellular Component	GO:0005886	plasma membrane	FOLH1	IDA		Human	PMID:12949938
Cellular Component	GO:0005886	plasma membrane	Folh1	IDA		Mouse	PMID:11210180
Biological Process	GO:0035609	C-terminal protein deglutamylation	FOLH1	IDA		Human	PMID:12949938
Biological Process	GO:0035609	C-terminal protein deglutamylation	FOLH1	IDA		Human	PMID:17241121
Biological Process	GO:0035609	C-terminal protein deglutamylation	FOLH1	IDA		Human	PMID:24863754
Biological Process	GO:0035609	C-terminal protein deglutamylation	FOLH1B	IDA		Human	PMID:17241121
Biological Process	GO:0006760	folic acid-containing compound metabolic process	Folh1	IDA		Mouse	PMID:11210180
Biological Process	GO:0043065	positive regulation of apoptotic process	Folh1	IMP		Rat	PMID:12876198|RGD:737756
Biological Process	GO:0030163	protein catabolic process	Folh1	IDA		Rat	PMID:9501243|RGD:728645
Biological Process	GO:0006508	proteolysis	FOLH1	IDA		Human	PMID:12949938
Biological Process	GO:0006508	proteolysis	Folh1	IDA		Mouse	PMID:21908619

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern