Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FGF3
  • Mouse genes Fgf3
  • Rat genes Fgf3
  • Zfish genes fgf3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fgf3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005104	fibroblast growth factor receptor binding	fgf3	IDA		Zfish	PMID:8622866
Molecular Function	GO:0005515	protein binding	FGF3	IPI	UniProtKB:P15880	Human	PMID:16263090
Molecular Function	GO:0005515	protein binding	Fgf3	IPI	UniProtKB:P15880	Mouse	MGI:MGI:3807762|PMID:16263090
Cellular Component	GO:0005737	cytoplasm	Fgf3	IDA		Mouse	PMID:7591288
Cellular Component	GO:0031012	extracellular matrix	fgf3	IDA		Zfish	PMID:8622866
Cellular Component	GO:0005615	extracellular space	fgf3	IDA		Zfish	PMID:8622866
Cellular Component	GO:0005794	Golgi apparatus	Fgf3	IDA		Mouse	PMID:7591288
Biological Process	GO:0021984	adenohypophysis development	fgf3	IMP	ZFIN:ZDB-MRPHLNO-041109-4	Zfish	PMID:18514643
Biological Process	GO:0009952	anterior/posterior pattern specification	fgf3	IGI	ZFIN:ZDB-GENE-020104-1,ZFIN:ZDB-GENE-990415-72	Zfish	PMID:15342476
Biological Process	GO:0051216	cartilage development	fgf3	IMP		Zfish	PMID:15509770
Biological Process	GO:0051216	cartilage development	fgf3	IMP	ZFIN:ZDB-MRPHLNO-041109-4	Zfish	PMID:14651935
Biological Process	GO:0051216	cartilage development	fgf3	IMP	ZFIN:ZDB-MRPHLNO-041109-4	Zfish	PMID:15327784
Biological Process	GO:0001708	cell fate specification	fgf3	IMP		Zfish	PMID:15262889
Biological Process	GO:0001708	cell fate specification	fgf3	IMP		Zfish	PMID:15228953
Biological Process	GO:0001708	cell fate specification	fgf3	IGI	ZFIN:ZDB-GENO-050209-17	Zfish	PMID:15262889
Biological Process	GO:0008283	cell population proliferation	fgf3	IMP	ZFIN:ZDB-GENO-071206-10	Zfish	PMID:30681411
Biological Process	GO:0009953	dorsal/ventral pattern formation	fgf3	IMP		Zfish	PMID:15228953
Biological Process	GO:0009953	dorsal/ventral pattern formation	fgf3	IMP		Zfish	PMID:15151985
Biological Process	GO:0009953	dorsal/ventral pattern formation	fgf3	IMP		Zfish	PMID:14757644
Biological Process	GO:0071696	ectodermal placode development	fgf3	IGI	ZFIN:ZDB-GENO-140402-3,ZFIN:ZDB-MRPHLNO-141230-19,ZFIN:ZDB-MRPHLNO-141230-20	Zfish	PMID:24677486
Biological Process	GO:0048702	embryonic neurocranium morphogenesis	fgf3	IGI	ZFIN:ZDB-GENE-990415-72	Zfish	PMID:27060628
Biological Process	GO:0009880	embryonic pattern specification	fgf3	IGI	ZFIN:ZDB-GENO-000731-1	Zfish	PMID:16873584
Biological Process	GO:0060059	embryonic retina morphogenesis in camera-type eye	fgf3	IGI	ZFIN:ZDB-GENO-070430-6,ZFIN:ZDB-MRPHLNO-050818-6	Zfish	PMID:19823566
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	FGF3	IGI	UniProtKB:P11362	Human	PMID:8663044
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	FGF3	IGI	UniProtKB:P21802	Human	PMID:8663044
Biological Process	GO:0008543	fibroblast growth factor receptor signaling pathway	Fgf3	IDA		Mouse	PMID:1376141
Biological Process	GO:0030902	hindbrain development	fgf3	IMP		Zfish	PMID:14745965
Biological Process	GO:0021854	hypothalamus development	fgf3	IMP	ZFIN:ZDB-MRPHLNO-191030-1	Zfish	PMID:31036752
Biological Process	GO:0021854	hypothalamus development	fgf3	IMP	ZFIN:ZDB-GENO-200415-1	Zfish	PMID:31036752
Biological Process	GO:0042472	inner ear morphogenesis	fgf3	IMP		Zfish	PMID:15228953
Biological Process	GO:0021703	locus ceruleus development	fgf3	IGI	ZFIN:ZDB-MRPHLNO-041109-5,ZFIN:ZDB-MRPHLNO-041109-6,ZFIN:ZDB-MRPHLNO-050818-3	Zfish	PMID:17215310
Biological Process	GO:0030901	midbrain development	fgf3	IGI	ZFIN:ZDB-MRPHLNO-041109-4,ZFIN:ZDB-MRPHLNO-050714-1	Zfish	PMID:23789101
Biological Process	GO:0043066	negative regulation of apoptotic process	fgf3	IMP	ZFIN:ZDB-GENO-050209-18	Zfish	PMID:15229178
Biological Process	GO:0055026	negative regulation of cardiac muscle tissue development	FGF3	IMP		Human	PMID:20702560
Biological Process	GO:0014032	neural crest cell development	fgf3	IMP	ZFIN:ZDB-MRPHLNO-041109-4	Zfish	PMID:23992145
Biological Process	GO:0021985	neurohypophysis development	fgf3	IMP	ZFIN:ZDB-GENO-141119-5	Zfish	PMID:23404108
Biological Process	GO:0048666	neuron development	fgf3	IGI	ZFIN:ZDB-GENO-150325-2	Zfish	PMID:25478689
Biological Process	GO:0048665	neuron fate specification	fgf3	IGI	ZFIN:ZDB-MRPHLNO-041109-4,ZFIN:ZDB-MRPHLNO-050714-1	Zfish	PMID:16256099
Biological Process	GO:0048709	oligodendrocyte differentiation	fgf3	IGI	ZFIN:ZDB-MRPHLNO-041109-4,ZFIN:ZDB-MRPHLNO-050714-1	Zfish	PMID:16256099
Biological Process	GO:0001759	organ induction	Fgf3	IGI	MGI:MGI:99604	Mouse	PMID:15741321
Biological Process	GO:0001759	organ induction	Fgf3	IGI	MGI:MGI:1099809	Mouse	PMID:12810586
Biological Process	GO:0043049	otic placode formation	fgf3	IMP		Zfish	PMID:14757644
Biological Process	GO:0043049	otic placode formation	fgf3	IGI	ZFIN:ZDB-GENE-990415-72	Zfish	PMID:12642489
Biological Process	GO:0043049	otic placode formation	fgf3	IMP	ZFIN:ZDB-GENO-070430-5	Zfish	PMID:17522161
Biological Process	GO:0043049	otic placode formation	fgf3	IGI	ZFIN:ZDB-GENO-070430-5,ZFIN:ZDB-MRPHLNO-060705-2	Zfish	PMID:17522161
Biological Process	GO:0043049	otic placode formation	fgf3	IMP		Zfish	PMID:15459102
Biological Process	GO:0071599	otic vesicle development	fgf3	IGI	ZFIN:ZDB-GENO-140402-3,ZFIN:ZDB-MRPHLNO-141230-19,ZFIN:ZDB-MRPHLNO-141230-20	Zfish	PMID:24677486
Biological Process	GO:0030916	otic vesicle formation	Fgf3	IGI	MGI:MGI:99604	Mouse	PMID:17601531
Biological Process	GO:0030916	otic vesicle formation	Fgf3	IGI	MGI:MGI:1099809	Mouse	PMID:17601531
Biological Process	GO:0030916	otic vesicle formation	fgf3	IMP		Zfish	PMID:14757644
Biological Process	GO:0030916	otic vesicle formation	fgf3	IGI	ZFIN:ZDB-GENE-990415-72	Zfish	PMID:15188428
Biological Process	GO:0048840	otolith development	fgf3	IGI	ZFIN:ZDB-GENO-070430-5,ZFIN:ZDB-GENO-070523-1	Zfish	PMID:17522161
Biological Process	GO:0007422	peripheral nervous system development	fgf3	IGI	ZFIN:ZDB-MRPHLNO-041109-5,ZFIN:ZDB-MRPHLNO-041109-6,ZFIN:ZDB-MRPHLNO-050818-3	Zfish	PMID:17215310
Biological Process	GO:0007422	peripheral nervous system development	fgf3	IGI	ZFIN:ZDB-GENO-070430-6	Zfish	PMID:17215310
Biological Process	GO:0030335	positive regulation of cell migration	fgf3	IGI	ZFIN:ZDB-GENO-980202-822	Zfish	PMID:15509770
Biological Process	GO:0008284	positive regulation of cell population proliferation	FGF3	IGI	UniProtKB:P11362	Human	PMID:8663044
Biological Process	GO:0008284	positive regulation of cell population proliferation	FGF3	IGI	UniProtKB:P21802	Human	PMID:8663044
Biological Process	GO:0008284	positive regulation of cell population proliferation	Fgf3	IDA		Mouse	PMID:1376141
Biological Process	GO:0050769	positive regulation of neurogenesis	fgf3	IMP	ZFIN:ZDB-MRPHLNO-050818-3	Zfish	PMID:16077091
Biological Process	GO:0045666	positive regulation of neuron differentiation	fgf3	IGI	ZFIN:ZDB-GENE-980526-474	Zfish	PMID:15262889
Biological Process	GO:0045666	positive regulation of neuron differentiation	fgf3	IMP		Zfish	PMID:15262889
Biological Process	GO:0030177	positive regulation of Wnt signaling pathway	fgf3	IGI	ZFIN:ZDB-GENE-990415-72	Zfish	PMID:14757644
Biological Process	GO:0036342	post-anal tail morphogenesis	Fgf3	IMP	MGI:MGI:3027990	Mouse	PMID:14623822
Biological Process	GO:0048920	posterior lateral line neuromast primordium migration	fgf3	IGI	ZFIN:ZDB-GENO-081211-4	Zfish	PMID:18599504
Biological Process	GO:0060041	retina development in camera-type eye	fgf3	IGI	ZFIN:ZDB-GENO-080710-8	Zfish	PMID:15809038
Biological Process	GO:0021571	rhombomere 5 development	fgf3	IGI	ZFIN:ZDB-MRPHLNO-050714-1,ZFIN:ZDB-MRPHLNO-050818-4	Zfish	PMID:12835397
Biological Process	GO:0021572	rhombomere 6 development	fgf3	IGI	ZFIN:ZDB-MRPHLNO-050714-1,ZFIN:ZDB-MRPHLNO-050818-4	Zfish	PMID:12835397
Biological Process	GO:0048752	semicircular canal morphogenesis	Fgf3	IGI	MGI:MGI:1099809	Mouse	PMID:17601531
Biological Process	GO:0001501	skeletal system development	fgf3	IMP		Zfish	PMID:15228953
Biological Process	GO:0048538	thymus development	Fgf3	IMP	MGI:MGI:3027990	Mouse	PMID:17000704
Biological Process	GO:0060118	vestibular receptor cell development	fgf3	IMP	ZFIN:ZDB-GENO-040716-10	Zfish	PMID:17013878
Biological Process	GO:0016055	Wnt signaling pathway	fgf3	IMP	ZFIN:ZDB-GENO-191205-24	Zfish	PMID:30681411

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern