Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FGD1
  • Mouse genes Fgd1
  • Rat genes Fgd1
  • Zfish genes fgd1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fgd1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	FGD1	IDA		Human	PMID:8969170
Molecular Function	GO:0005515	protein binding	Fgd1	IPI	PR:Q60598	Mouse	PMID:12913069
Molecular Function	GO:0005515	protein binding	Fgd1	IPI	PR:Q62418	Mouse	PMID:12913069
Molecular Function	GO:0005515	protein binding	Fgd1	IPI	PR:Q640L3	Mouse	PMID:17000758
Molecular Function	GO:0031267	small GTPase binding	FGD1	IDA		Human	PMID:8969170
Cellular Component	GO:0005737	cytoplasm	Fgd1	IDA		Mouse	PMID:12913069
Cellular Component	GO:0005794	Golgi apparatus	Fgd1	IDA		Mouse	PMID:12913069
Cellular Component	GO:0030027	lamellipodium	Fgd1	IDA		Mouse	PMID:12913069
Cellular Component	GO:0001726	ruffle	Fgd1	IDA		Mouse	PMID:12913069
Biological Process	GO:0030036	actin cytoskeleton organization	FGD1	IDA		Human	PMID:8969170
Biological Process	GO:0007010	cytoskeleton organization	Fgd1	IDA		Mouse	PMID:12913069
Biological Process	GO:0046847	filopodium assembly	FGD1	IDA		Human	PMID:8969170
Biological Process	GO:0008360	regulation of cell shape	Fgd1	IDA		Mouse	MGI:MGI:2671745|PMID:12913069
Biological Process	GO:0043087	regulation of GTPase activity	FGD1	IDA		Human	PMID:8969170

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern