Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FEZF2
  • Mouse genes Fezf2
  • Rat genes Fezf2
  • Zfish genes fezf2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fezf2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Fezf2	IDA		Mouse	PMID:24997765
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Fezf2	IDA		Mouse	PMID:24997765
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Fezf2	IDA		Mouse	PMID:24997765
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Fezf2	IDA		Mouse	PMID:20431123
Molecular Function	GO:0043565	sequence-specific DNA binding	Fezf2	IDA		Mouse	MGI:MGI:5908758|PMID:28245922
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Fezf2	IDA		Mouse	MGI:MGI:5908758|PMID:28245922
Biological Process	GO:0007413	axonal fasciculation	Fezf2	IMP	MGI:MGI:3046867	Mouse	PMID:16284245
Biological Process	GO:0043697	cell dedifferentiation	Fezf2	IGI	UniProtKB:Q9VQ56	Mouse	MGI:MGI:5905549|PMID:20152183
Biological Process	GO:0021954	central nervous system neuron development	fezf2	IMP	ZFIN:ZDB-GENO-070129-9	Zfish	PMID:10191060
Biological Process	GO:0021853	cerebral cortex GABAergic interneuron migration	Fezf2	IMP	MGI:MGI:3046867	Mouse	PMID:21338885
Biological Process	GO:0021895	cerebral cortex neuron differentiation	Fezf2	IMP	MGI:MGI:3046867	Mouse	PMID:21338885
Biological Process	GO:0071679	commissural neuron axon guidance	fezf2	IMP	ZFIN:ZDB-MRPHLNO-070129-7	Zfish	PMID:21471212
Biological Process	GO:0071679	commissural neuron axon guidance	fezf2	IMP	ZFIN:ZDB-GENO-110701-16	Zfish	PMID:21471212
Biological Process	GO:0021902	commitment of neuronal cell to specific neuron type in forebrain	Fezf2	IMP	MGI:MGI:3046867	Mouse	PMID:21338885
Biological Process	GO:0016358	dendrite development	Fezf2	IMP		Mouse	PMID:16314561
Biological Process	GO:0021542	dentate gyrus development	Fezf2	IMP	MGI:MGI:3046867	Mouse	PMID:16971467
Biological Process	GO:0021536	diencephalon development	fezf2	IMP	ZFIN:ZDB-GENO-070706-5	Zfish	PMID:17164418
Biological Process	GO:0021536	diencephalon development	fezf2	IMP	ZFIN:ZDB-MRPHLNO-070129-6	Zfish	PMID:17164418
Biological Process	GO:0021536	diencephalon development	fezf2	IMP	ZFIN:ZDB-MRPHLNO-070129-7	Zfish	PMID:17164418
Biological Process	GO:0021797	forebrain anterior/posterior pattern specification	Fezf2	IGI	MGI:MGI:1920441	Mouse	PMID:16971467
Biological Process	GO:0030900	forebrain development	Fezf2	IMP	MGI:MGI:3046867	Mouse	PMID:16284245
Biological Process	GO:0030900	forebrain development	Fezf2	IMP	MGI:MGI:3046867	Mouse	PMID:15188439
Biological Process	GO:0030900	forebrain development	fezf2	IMP	ZFIN:ZDB-GENO-070129-9	Zfish	PMID:12469125
Biological Process	GO:0030900	forebrain development	fezf2	IMP		Zfish	PMID:12469125
Biological Process	GO:0021879	forebrain neuron differentiation	fezf2	IMP	ZFIN:ZDB-GENO-070129-9	Zfish	PMID:18799544
Biological Process	GO:0097154	GABAergic neuron differentiation	Fezf2	IDA		Mouse	PMID:24997765
Biological Process	GO:0021854	hypothalamus development	fezf2	IMP	ZFIN:ZDB-GENO-070129-9,ZFIN:ZDB-MRPHLNO-070129-7,ZFIN:ZDB-MRPHLNO-080414-2	Zfish	PMID:18003738
Biological Process	GO:0021854	hypothalamus development	fezf2	IMP	ZFIN:ZDB-GENO-070129-9	Zfish	PMID:18003738
Biological Process	GO:0007626	locomotory behavior	Fezf2	IMP	MGI:MGI:3525887	Mouse	PMID:16284245
Biological Process	GO:0007626	locomotory behavior	Fezf2	IMP	MGI:MGI:3046867	Mouse	PMID:15188439
Biological Process	GO:0021767	mammillary body development	fezf2	IMP	ZFIN:ZDB-MRPHLNO-070129-7	Zfish	PMID:23533176
Biological Process	GO:0008285	negative regulation of cell population proliferation	Fezf2	IMP		Mouse	MGI:MGI:4454201|PMID:20431123
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	fezf2	IMP		Zfish	PMID:12469125
Biological Process	GO:0045665	negative regulation of neuron differentiation	Fezf2	IDA		Mouse	PMID:24997765
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Fezf2	IDA		Mouse	PMID:20431123
Biological Process	GO:0007399	nervous system development	fezf2	IMP	ZFIN:ZDB-GENO-070129-9	Zfish	PMID:15219677
Biological Process	GO:0030182	neuron differentiation	Fezf2	IGI	MGI:MGI:1920441	Mouse	PMID:20431123
Biological Process	GO:0030182	neuron differentiation	Fezf2	IGI	MGI:MGI:104876	Mouse	PMID:20431123
Biological Process	GO:0048664	neuron fate determination	Fezf2	IDA		Mouse	PMID:24997765
Biological Process	GO:0097150	neuronal stem cell population maintenance	fezf2	IMP	ZFIN:ZDB-GENO-150707-6	Zfish	PMID:25319688
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Fezf2	IMP		Mouse	MGI:MGI:4454201|PMID:20431123
Biological Process	GO:0045666	positive regulation of neuron differentiation	Fezf2	IGI	MGI:MGI:1920441	Mouse	PMID:20431123
Biological Process	GO:0045666	positive regulation of neuron differentiation	Fezf2	IGI	MGI:MGI:104876	Mouse	PMID:20431123
Biological Process	GO:1902667	regulation of axon guidance	Fezf2	IMP		Mouse	PMID:16314561
Biological Process	GO:1902667	regulation of axon guidance	Fezf2	IMP	MGI:MGI:3046867	Mouse	PMID:16284245
Biological Process	GO:1902667	regulation of axon guidance	Fezf2	IMP	MGI:MGI:3525887	Mouse	PMID:24997765
Biological Process	GO:0050767	regulation of neurogenesis	Fezf2	IGI	UniProtKB:Q9VQ56	Mouse	MGI:MGI:5905549|PMID:20152183
Biological Process	GO:0008593	regulation of Notch signaling pathway	fezf2	IMP	ZFIN:ZDB-GENO-150707-6	Zfish	PMID:25319688
Biological Process	GO:0021537	telencephalon development	Fezf2	IMP		Mouse	MGI:MGI:4454201|PMID:20431123
Biological Process	GO:0021537	telencephalon development	Fezf2	IGI	MGI:MGI:1920441	Mouse	PMID:20431123
Biological Process	GO:0021537	telencephalon development	Fezf2	IGI	MGI:MGI:104876	Mouse	PMID:20431123

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern