Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FEZF1
  • Mouse genes Fezf1
  • Rat genes Fezf1
  • Zfish genes fezf1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fezf1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	Fezf1	IMP		Mouse	MGI:MGI:4454201|PMID:20431123
Molecular Function	GO:0005515	protein binding	FEZF1	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FEZF1	IPI	UniProtKB:P60410	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FEZF1	IPI	UniProtKB:Q07627	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FEZF1	IPI	UniProtKB:Q5TD97	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FEZF1	IPI	UniProtKB:Q6A162	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FEZF1	IPI	UniProtKB:Q99750	Human	PMID:32296183
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Fezf1	IDA		Mouse	PMID:20431123
Molecular Function	GO:0043565	sequence-specific DNA binding	Fezf1	IDA		Mouse	MGI:MGI:5908758|PMID:28245922
Molecular Function	GO:0000976	transcription cis-regulatory region binding	Fezf1	IDA		Mouse	MGI:MGI:5908758|PMID:28245922
Cellular Component	GO:0005829	cytosol	FEZF1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	FEZF1	IDA		Human	GO_REF:0000052
Biological Process	GO:0007411	axon guidance	Fezf1	IMP		Mouse	PMID:16540508
Biological Process	GO:0043697	cell dedifferentiation	Fezf1	IGI	UniProtKB:Q9VQ56	Mouse	MGI:MGI:5905549|PMID:20152183
Biological Process	GO:0021797	forebrain anterior/posterior pattern specification	Fezf1	IGI	MGI:MGI:1859823	Mouse	PMID:16971467
Biological Process	GO:0030900	forebrain development	Fezf1	IMP		Mouse	PMID:16540508
Biological Process	GO:1904936	interneuron migration	Fezf1	IMP		Mouse	PMID:16540508
Biological Process	GO:0008285	negative regulation of cell population proliferation	Fezf1	IMP		Mouse	MGI:MGI:4454201|PMID:20431123
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Fezf1	IMP		Mouse	MGI:MGI:4454201|PMID:20431123
Biological Process	GO:0030182	neuron differentiation	Fezf1	IGI	MGI:MGI:1859823	Mouse	PMID:20431123
Biological Process	GO:0021772	olfactory bulb development	Fezf1	IMP	MGI:MGI:3626294	Mouse	PMID:16971467
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Fezf1	IMP		Mouse	MGI:MGI:4454201|PMID:20431123
Biological Process	GO:0045666	positive regulation of neuron differentiation	Fezf1	IGI	MGI:MGI:1859823	Mouse	PMID:20431123
Biological Process	GO:0050767	regulation of neurogenesis	Fezf1	IGI	UniProtKB:Q9VQ56	Mouse	MGI:MGI:5905549|PMID:20152183
Biological Process	GO:0021537	telencephalon development	Fezf1	IMP		Mouse	MGI:MGI:4454201|PMID:20431123

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern