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Fezf1 Gene Detail
Summary
  • Symbol
    Fezf1
  • Name
    Fez family zinc finger 1
  • Synonyms
    3110069A13Rik, Fez, Zfp312-like
  • Feature Type
    protein coding gene
  • IDs
    MGI:1920441
    NCBI Gene: 73191
  • Gene Overview
    MyGene.info: FEZF1
  • Alliance
Location & Maps
more
  • Sequence Map
    Chr6:23245044-23248362 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      3319 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 6, 10.55 cM, cytoband A3
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    FEZF1, FEZ family zinc finger 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    FEZF1, FEZ family zinc finger 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FEZ, HH22, ZNF312B
  • Links
    NCBI Gene ID: 389549
    neXtProt AC: NX_A0PJY2
    UniProt: A0PJY2

  • Chr Location
    7q31.32; chr7:122300939-122311855 (-)  GRCh38.p7

Human Diseases
more
  • Diseases
    2 with human FEZF1 associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    13 phenotypes from 5 alleles in 5 genetic backgrounds
    11 phenotypes from multigenic genotypes
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for a null mutation of this gene display neonatal lethality, impaired olfactory bulb development and impaired olfactory bulb interneuron migration.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic OTTMUSG00000055954 VEGA Gene Model | MGI Sequence Detail 3319 C57BL/6J ±  kb
    transcript OTTMUST00000138429 VEGA | MGI Sequence Detail 2409 Not Applicable  
    polypeptide OTTMUSP00000072789 VEGA | MGI Sequence Detail 475 Not Applicable  
    For the selected sequence
    Polymorphisms
    less
    • SNPs within 2kb
      52 from dbSNP Build 142
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 11
      cDNA 9
      Primer pair 2

      Microarray probesets 3
    References
    more
    • Summaries
      All 51
      Developmental Gene Expression 21
      Gene Ontology 8
      Phenotypes 9
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:256883 Zhou J, et al., Conserved expression of ultra-conserved noncoding RNA in mammalian nervous system. Biochim Biophys Acta. 2017 Dec;1860(12):1159-1168

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    06/12/2018
    MGI 6.12
    The Jackson Laboratory