Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FEV
  • Mouse genes Fev
  • Rat genes Fev
  • Zfish genes fev
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fev

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Fev	IDA		Rat	PMID:9468386|RGD:633697
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Fev	IDA		Rat	PMID:9468386|RGD:633697
Molecular Function	GO:0003690	double-stranded DNA binding	Fev	IDA		Rat	PMID:9468386|RGD:633697
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Fev	IDA		Rat	PMID:9468386|RGD:633697
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	FEV	IDA		Human	PMID:28473536
Molecular Function	GO:0000976	transcription cis-regulatory region binding	fev	IDA		Zfish	PMID:23591790
Cellular Component	GO:0016607	nuclear speck	FEV	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Fev	IDA		Mouse	PMID:11875656
Biological Process	GO:0003158	endothelium development	fev	IMP	ZFIN:ZDB-FISH-150901-15091	Zfish	PMID:32231307
Biological Process	GO:0060218	hematopoietic stem cell differentiation	fev	IMP	ZFIN:ZDB-MRPHLNO-140321-5	Zfish	PMID:23591790
Biological Process	GO:0060218	hematopoietic stem cell differentiation	fev	IMP	ZFIN:ZDB-GENO-140807-2	Zfish	PMID:23591790
Biological Process	GO:0048665	neuron fate specification	Fev	IMP	MGI:MGI:2449922	Mouse	PMID:20818386
Biological Process	GO:0042551	neuron maturation	Fev	IMP	MGI:MGI:2449922	Mouse	PMID:20818386
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Fev	IDA		Rat	PMID:9468386|RGD:633697
Biological Process	GO:0010628	positive regulation of gene expression	Fev	IMP	MGI:MGI:2449922	Mouse	PMID:20818386
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Fev	IDA		Rat	PMID:9468386|RGD:633697
Biological Process	GO:0006355	regulation of DNA-templated transcription	fev	IDA		Zfish	PMID:23591790

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern