Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FBXO6
  • Mouse genes Fbxo6
  • Rat genes Fbxo6
  • Zfish genes fbxo6.1,fbxo6.2,fbxo6.3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fbxo6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030246	carbohydrate binding	Fbxo6	IDA		Mouse	PMID:12939278
Molecular Function	GO:0005515	protein binding	FBXO6	IPI	UniProtKB:O14757	Human	PMID:19716789
Molecular Function	GO:0005515	protein binding	FBXO6	IPI	UniProtKB:Q13616	Human	PMID:23108047
Molecular Function	GO:0005515	protein binding	FBXO6	IPI	UniProtKB:P63208	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	FBXO6	IPI	UniProtKB:Q13616	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	FBXO6	IPI	UniProtKB:P63208	Human	PMID:30833792
Molecular Function	GO:0005515	protein binding	FBXO6	IPI	UniProtKB:Q08380	Human	PMID:30833792
Molecular Function	GO:0005515	protein binding	FBXO6	IPI	UniProtKB:Q13616	Human	PMID:30833792
Molecular Function	GO:0005515	protein binding	FBXO6	IPI	UniProtKB:P63208	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Fbxo6	IDA		Mouse	MGI:MGI:2679753|PMID:12939278
Molecular Function	GO:0005515	protein binding	Fbxo6	IDA		Mouse	MGI:MGI:5644019|PMID:21062743
Molecular Function	GO:0005515	protein binding	Fbxo6	IPI	PR:Q01853	Mouse	PMID:15723043
Molecular Function	GO:0061630	ubiquitin protein ligase activity	Fbxo6	IDA		Mouse	PMID:12939278
Cellular Component	GO:0005737	cytoplasm	FBXO6	IDA		Human	PMID:19716789
Cellular Component	GO:0044322	endoplasmic reticulum quality control compartment	Fbxo6	IDA		Mouse	MGI:MGI:5644019|PMID:21062743
Cellular Component	GO:0044322	endoplasmic reticulum quality control compartment	Fbxo6	IDA		Mouse	MGI:MGI:6467686|PMID:23233672
Cellular Component	GO:0019005	SCF ubiquitin ligase complex	FBXO6	IDA		Human	PMID:19716789
Cellular Component	GO:0019005	SCF ubiquitin ligase complex	Fbxo6	IDA		Mouse	MGI:MGI:2679753|PMID:12939278
Biological Process	GO:0006516	glycoprotein catabolic process	Fbxo6	IDA		Mouse	PMID:15723043
Biological Process	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	FBXO6	IDA		Human	PMID:19716789
Biological Process	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	Fbxo6	IDA		Mouse	MGI:MGI:2679753|PMID:12939278
Biological Process	GO:0030433	ubiquitin-dependent ERAD pathway	Fbxo6	IMP		Mouse	MGI:MGI:2679753|PMID:12939278

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern