Fbxo6
Gene Detail

Symbol Name ID

Fbxo6 F-box protein 6 MGI:1354743

Synonyms

FBG2, Fbs2, Fbx6b, Fbxo6b

Feature Type

protein coding gene

Genetic Map

Chromosome 4

78.67 cM
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr4:148145716-148152140 bp, - strand From VEGA annotation of GRCm38   6425 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:9274  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 7 zebrafish

Gene Tree: Fbxo6

Human homologs

Human Homolog		FBXO6, F-box protein 6
NCBI Gene ID		26270
neXtProt AC		NX_Q9NRD1
Human Synonyms		FBG2, FBS2, FBX6, Fbx6b
Human Chr (Location)		1p36.22; chr1:11724150-11734411 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(63) : Targeted(1) Gene trapped(62)

Gene Ontology (GO) classifications

All GO classifications: (16 annotations)

Process	DNA repair, ER-associated protein catabolic process, ...
Component	cytoplasm, SCF ubiquitin ligase complex
Function	carbohydrate binding, glycoprotein binding, ...

External Resources: FuncBase

Expression

Literature Summary: (1 records)
Data Summary: Results (17)    Tissues (13)    Images (1)
Theiler Stages: 21, 28

Assay Type	Results
Northern blot	17

cDNA source data(73)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(73) cDNA(73)
Microarray probesets(5)

Other database links

VEGA Gene Model	OTTMUSG00000010945 (Evidence)
Ensembl Gene Model	ENSMUSG00000055401 (Evidence)
Entrez Gene	50762 (Evidence)
UniGene	27445
DFCI	TC1577174, TC1643549, TC1688276, TC1749968
DoTS	DT.101373636, DT.534686, DT.94122572, DT.97372417, DT.97372419, DT.97372420
NIA Mouse Gene Index	U025786
Consensus CDS Project	CCDS18933.1
International Mouse Knockout Project Status	Fbxo6

Sequences

Length	Strain/Species
genomic	OTTMUSG00000010945	VEGA Gene Model | MGI Sequence Detail	6425	C57BL/6J
transcript	OTTMUST00000070120	VEGA | MGI Sequence Detail	1938	Not Applicable
polypeptide	OTTMUSP00000035702	VEGA | MGI Sequence Detail	295	Not Applicable

All sequences(78) RefSeq(10) UniProt(4)

Polymorphisms

SNPs(74 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR007397	F-box associated (FBA) domain
InterPro	IPR001810	F-box domain, cyclin-like
InterPro	IPR008979	Galactose-binding domain-like
Protein Ontology	PR:000007418	F-box only protein 6

References

(Earliest) J:58149 Winston JT, et al., A family of mammalian F-box proteins. Curr Biol. 1999 Oct 21;9(20):1180-2
(Latest) J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9
All references(33)

Other accession IDs

MGI:2140136