Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FBXL7
  • Mouse genes Fbxl7
  • Rat genes Fbxl7
  • Zfish genes fbxl7,si:dkey-192l18.9
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fbxl7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	FBXL7	IPI	UniProtKB:O15392	Human	PMID:25778398
Molecular Function	GO:0005515	protein binding	FBXL7	IPI	UniProtKB:O15392	Human	PMID:28218735
Molecular Function	GO:0005515	protein binding	FBXL7	IPI	UniProtKB:A0A0C3SFZ9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FBXL7	IPI	UniProtKB:Q92609	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Fbxl7	IPI	UniProtKB:O14965	Mouse	MGI:MGI:5426128|PMID:22306998
Molecular Function	GO:0005515	protein binding	Fbxl7	IPI	UniProtKB:O70201	Mouse	MGI:MGI:6368091|PMID:25778398
Cellular Component	GO:0005813	centrosome	Fbxl7	IDA		Mouse	MGI:MGI:5426128|PMID:22306998
Cellular Component	GO:0019005	SCF ubiquitin ligase complex	FBXL7	IDA		Human	PMID:25778398
Cellular Component	GO:0019005	SCF ubiquitin ligase complex	Fbxl7	IDA		Mouse	MGI:MGI:5426128|PMID:22306998
Biological Process	GO:0000086	G2/M transition of mitotic cell cycle	Fbxl7	IDA		Mouse	MGI:MGI:5426128|PMID:22306998
Biological Process	GO:0000278	mitotic cell cycle	Fbxl7	IMP		Mouse	MGI:MGI:5426128|PMID:22306998
Biological Process	GO:0000209	protein polyubiquitination	FBXL7	IDA		Human	PMID:25778398
Biological Process	GO:0000209	protein polyubiquitination	FBXL7	IMP		Human	PMID:28218735
Biological Process	GO:0000209	protein polyubiquitination	Fbxl7	IMP		Mouse	MGI:MGI:6368091|PMID:25778398
Biological Process	GO:0016567	protein ubiquitination	Fbxl7	IDA		Mouse	MGI:MGI:5426128|PMID:22306998
Biological Process	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	FBXL7	IDA		Human	PMID:25778398
Biological Process	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	FBXL7	IMP		Human	PMID:28218735
Biological Process	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	Fbxl7	IMP		Mouse	MGI:MGI:6368091|PMID:25778398
Biological Process	GO:0031146	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	Fbxl7	IMP		Mouse	MGI:MGI:5426128|PMID:22306998

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern