Fbxl7
Gene Detail

Symbol Name ID

Fbxl7 F-box and leucine-rich repeat protein 7 MGI:3052506

Synonyms

D230018M15Rik, Fbl6, FBL7

Feature Type

protein coding gene

Genetic Map

Chromosome 15

9.87 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr15:26543084-26895049 bp, - strand From Ensembl annotation of GRCm38   351966 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:69121  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Fbxl7

Human homologs

Human Homolog		FBXL7, F-box and leucine-rich repeat protein 7
NCBI Gene ID		23194
neXtProt AC		NX_Q9UJT9
Human Synonyms		FBL6, FBL7
Human Chr (Location)		5p15.1; chr5:15500305-15939900 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(4) : Targeted(2) Gene trapped(2)

Gene Ontology (GO) classifications

All GO classifications: (12 annotations)

Process	cell cycle, cell division, ...
Component	centrosome, cytoplasm, ...
Function	protein binding

External Resources: FuncBase

Expression

cDNA source data(21)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(21) cDNA(21)
Microarray probesets(7)

Other database links

Ensembl Gene Model	ENSMUSG00000043556 (Evidence)
Entrez Gene	448987 (Evidence)
UniGene	253378
DFCI	TC1590764, TC1598105, TC1598121, TC1671116
DoTS	DT.101320743, DT.91379051
NIA Mouse Gene Index	U036047, U036048
Consensus CDS Project	CCDS37052.1
International Mouse Knockout Project Status	Fbxl7

Sequences

Length	Strain/Species
genomic	ENSMUSG00000043556	Ensembl Gene Model | MGI Sequence Detail	351966	C57BL/6J
transcript	ENSMUST00000059204	Ensembl | MGI Sequence Detail	1476	Not Applicable
polypeptide	ENSMUSP00000061305	Ensembl | MGI Sequence Detail	491	Not Applicable

All sequences(30) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(1762 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001810	F-box domain, cyclin-like
InterPro	IPR006553	Leucine-rich repeat, cysteine-containing subtype
Protein Ontology	PR:000007385	F-box/LRR-repeat protein 7

References

(Earliest) J:80000 The FANTOM Consortium and The RIKEN Genome Exploration Research Group Phase I & II Team, Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Nature. 2002;420:563-573
(Latest) J:184734 Coon TA, et al., Novel E3 ligase component FBXL7 ubiquitinates and degrades Aurora A, causing mitotic arrest. Cell Cycle. 2012 Feb 15;11(4):721-9
All references(29)

Other accession IDs

MGI:2146117, MGI:2442376