Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FANCC
  • Mouse genes Fancc
  • Rat genes Fancc
  • Zfish genes fancc
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Fancc

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	FANCC	IPI	UniProtKB:Q6FHY5	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	FANCC	IPI	UniProtKB:P14625	Human	PMID:9596688
Cellular Component	GO:0000785	chromatin	FANCC	IDA		Human	PMID:22343915
Cellular Component	GO:0000785	chromatin	Fancc	IDA		Rat	PMID:15256425|RGD:1342450
Cellular Component	GO:0005829	cytosol	FANCC	IDA		Human	PMID:9596688
Cellular Component	GO:0043240	Fanconi anaemia nuclear complex	FANCC	IDA		Human	PMID:20347428
Cellular Component	GO:0043240	Fanconi anaemia nuclear complex	FANCC	IDA		Human	PMID:22266823
Biological Process	GO:0048854	brain morphogenesis	Fancc	IGI	MGI:MGI:1890081	Mouse	PMID:24483844
Biological Process	GO:0034599	cellular response to oxidative stress	Fancc	IGI	MGI:MGI:1890081	Mouse	PMID:24483844
Biological Process	GO:0007276	gamete generation	Fancc	IMP	MGI:MGI:1858040	Mouse	PMID:8630504
Biological Process	GO:0007281	germ cell development	Fancc	IMP	MGI:MGI:1858041	Mouse	PMID:8704201
Biological Process	GO:0002262	myeloid cell homeostasis	Fancc	IGI	MGI:MGI:98351	Mouse	PMID:11493445
Biological Process	GO:0002262	myeloid cell homeostasis	Fancc	IMP	MGI:MGI:1858040	Mouse	PMID:11493445
Biological Process	GO:0097150	neuronal stem cell population maintenance	Fancc	IGI	MGI:MGI:1890081	Mouse	PMID:24483844
Biological Process	GO:0006289	nucleotide-excision repair	Fancc	IMP	MGI:MGI:1858041	Mouse	PMID:8704201
Biological Process	GO:0006513	protein monoubiquitination	FANCC	IDA		Human	PMID:24910428
Biological Process	GO:0019430	removal of superoxide radicals	Fancc	IGI	MGI:MGI:98351	Mouse	PMID:11493445

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern