Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FAIM2
  • Mouse genes Faim2
  • Rat genes Faim2
  • Zfish genes faim2a,faim2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Faim2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	FAIM2	IPI	UniProtKB:O95208-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FAIM2	IPI	UniProtKB:Q6P531	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Faim2	IPI	PR:Q64373	Mouse	PMID:26582200
Cellular Component	GO:0005783	endoplasmic reticulum	Faim2	IDA		Mouse	PMID:26582200
Cellular Component	GO:0005794	Golgi apparatus	Faim2	IDA		Mouse	PMID:26582200
Cellular Component	GO:0016020	membrane	Faim2	IDA		Mouse	PMID:26582200
Cellular Component	GO:0045121	membrane raft	FAIM2	IDA		Human	PMID:17635665
Cellular Component	GO:0045121	membrane raft	Faim2	IDA		Mouse	MGI:MGI:5315338|PMID:17635665
Biological Process	GO:0097190	apoptotic signaling pathway	Faim2	IMP	MGI:MGI:4888719	Mouse	PMID:21209208
Biological Process	GO:0007417	central nervous system development	Faim2	IEP		Rat	PMID:9698393|RGD:633222
Biological Process	GO:0021681	cerebellar granular layer development	Faim2	IMP		Mouse	MGI:MGI:5295128|PMID:21957071
Biological Process	GO:0021702	cerebellar Purkinje cell differentiation	Faim2	IMP		Mouse	MGI:MGI:5295128|PMID:21957071
Biological Process	GO:0021680	cerebellar Purkinje cell layer development	Faim2	IMP		Mouse	MGI:MGI:5295128|PMID:21957071
Biological Process	GO:0021549	cerebellum development	Faim2	IMP		Mouse	MGI:MGI:5295128|PMID:21957071
Biological Process	GO:2001234	negative regulation of apoptotic signaling pathway	Faim2	IMP	MGI:MGI:4888719	Mouse	PMID:21209208
Biological Process	GO:1902042	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	FAIM2	IDA		Human	PMID:26582200
Biological Process	GO:0043524	negative regulation of neuron apoptotic process	Faim2	IMP	MGI:MGI:4888719	Mouse	PMID:21209208
Biological Process	GO:0051402	neuron apoptotic process	Faim2	IMP	MGI:MGI:4888719	Mouse	PMID:21209208
Biological Process	GO:0043523	regulation of neuron apoptotic process	FAIM2	IMP		Human	PMID:17635665
Biological Process	GO:0043523	regulation of neuron apoptotic process	Faim2	IMP		Mouse	MGI:MGI:5315338|PMID:17635665
Biological Process	GO:0043523	regulation of neuron apoptotic process	Faim2	IMP		Mouse	MGI:MGI:5295128|PMID:21957071
Biological Process	GO:0002931	response to ischemia	Faim2	IMP	MGI:MGI:4888719	Mouse	PMID:21209208

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern