Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes FAF1
  • Mouse genes Faf1
  • Rat genes Faf1
  • Zfish genes faf1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Faf1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0031072	heat shock protein binding	FAF1	IDA		Human	PMID:15596450
Molecular Function	GO:0051059	NF-kappaB binding	FAF1	IPI	UniProtKB:Q04206	Human	PMID:14600157
Molecular Function	GO:0005515	protein binding	FAF1	IPI	UniProtKB:O75618	Human	PMID:15688372
Molecular Function	GO:0005515	protein binding	FAF1	IPI	UniProtKB:Q13158	Human	PMID:15688372
Molecular Function	GO:0005515	protein binding	FAF1	IPI	UniProtKB:P55072	Human	PMID:15743842
Molecular Function	GO:0005515	protein binding	FAF1	IPI	UniProtKB:P55072,UniProtKB:Q9H211	Human	PMID:26842564
Molecular Function	GO:0005515	protein binding	FAF1	IPI	UniProtKB:Q7Z739	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	FAF1	IPI	UniProtKB:P28799	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	FAF1	IPI	UniProtKB:Q7Z699	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Faf1	IPI	PR:P25446	Mouse	PMID:8524870
Molecular Function	GO:0019904	protein domain specific binding	Faf1	IPI	PR:P25446	Mouse	PMID:8524870
Molecular Function	GO:0019901	protein kinase binding	FAF1	IDA		Human	PMID:11713579
Molecular Function	GO:0043130	ubiquitin binding	FAF1	IDA		Human	PMID:18775313
Molecular Function	GO:0031625	ubiquitin protein ligase binding	FAF1	IDA		Human	PMID:18775313
Cellular Component	GO:0005737	cytoplasm	Faf1	IDA		Mouse	PMID:11731229
Cellular Component	GO:0005829	cytosol	FAF1	IDA		Human	PMID:15596450
Cellular Component	GO:0005635	nuclear envelope	Faf1	IDA		Mouse	PMID:11731229
Cellular Component	GO:0005654	nucleoplasm	FAF1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	FAF1	IDA		Human	PMID:15596450
Cellular Component	GO:0005634	nucleus	FAF1	IDA		Human	PMID:26842564
Cellular Component	GO:1990917	ooplasm	Faf1	IDA		Mouse	PMID:11731229
Cellular Component	GO:0048471	perinuclear region of cytoplasm	FAF1	IDA		Human	PMID:11713579
Cellular Component	GO:0034098	VCP-NPL4-UFD1 AAA ATPase complex	FAF1	IDA		Human	PMID:18775313
Biological Process	GO:0051216	cartilage development	faf1	IMP	ZFIN:ZDB-MRPHLNO-110221-2	Zfish	PMID:21295280
Biological Process	GO:0051216	cartilage development	faf1	IMP	ZFIN:ZDB-MRPHLNO-110221-1	Zfish	PMID:21295280
Biological Process	GO:0008219	cell death	FAF1	IMP		Human	PMID:15743842
Biological Process	GO:0007253	cytoplasmic sequestering of NF-kappaB	FAF1	IMP		Human	PMID:14600157
Biological Process	GO:0031101	fin regeneration	faf1	IMP	ZFIN:ZDB-GENO-190104-1	Zfish	PMID:28871129
Biological Process	GO:0060037	pharyngeal system development	faf1	IMP	ZFIN:ZDB-MRPHLNO-110221-1	Zfish	PMID:21295280
Biological Process	GO:0060037	pharyngeal system development	faf1	IMP		Zfish	PMID:21295280
Biological Process	GO:0010942	positive regulation of cell death	FAF1	IDA		Human	PMID:15596450
Biological Process	GO:0045740	positive regulation of DNA replication	FAF1	IMP		Human	PMID:26842564
Biological Process	GO:1902043	positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	Faf1	IDA		Mouse	PMID:8524870
Biological Process	GO:0045732	positive regulation of protein catabolic process	FAF1	IMP		Human	PMID:26842564
Biological Process	GO:0031334	positive regulation of protein-containing complex assembly	FAF1	IMP		Human	PMID:15688372
Biological Process	GO:0030155	regulation of cell adhesion	Faf1	IMP		Mouse	PMID:11731229
Biological Process	GO:0042176	regulation of protein catabolic process	FAF1	IMP		Human	PMID:15743842

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern