Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ESRRG
  • Mouse genes Esrrg
  • Rat genes Esrrg
  • Zfish genes esrrga,esrrgb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Esrrg

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Esrrg	IMP		Mouse	MGI:MGI:5572884|PMID:15149736
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Esrrg	IDA		Mouse	MGI:MGI:1342114|PMID:10428842
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Esrrg	IDA		Mouse	MGI:MGI:5572884|PMID:15149736
Molecular Function	GO:0003700	DNA-binding transcription factor activity	esrrga	IDA		Zfish	PMID:15088146
Molecular Function	GO:0034056	estrogen response element binding	Esrrg	IDA		Mouse	MGI:MGI:1342114|PMID:10428842
Molecular Function	GO:0005515	protein binding	ESRRG	IPI	UniProtKB:Q61026	Human	PMID:10428842
Molecular Function	GO:0005515	protein binding	ESRRG	IPI	UniProtKB:Q9UBK2	Human	PMID:18063693
Molecular Function	GO:0005515	protein binding	ESRRG	IPI	UniProtKB:Q9UBK2	Human	PMID:19171140
Molecular Function	GO:0005515	protein binding	ESRRG	IPI	UniProtKB:Q9UBK2	Human	PMID:19914244
Molecular Function	GO:0005515	protein binding	ESRRG	IPI	UniProtKB:A0MZ66	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ESRRG	IPI	UniProtKB:G2XKQ0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ESRRG	IPI	UniProtKB:P50222	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ESRRG	IPI	UniProtKB:P51843	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ESRRG	IPI	UniProtKB:Q05D60	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ESRRG	IPI	UniProtKB:Q12769	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ESRRG	IPI	UniProtKB:Q9BVG8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Esrrg	IPI	UniProtKB:Q91ZR3	Mouse	MGI:MGI:4436999|PMID:19690166
Molecular Function	GO:0005515	protein binding	Esrrg	IPI	UniProtKB:Q61026	Mouse	MGI:MGI:1342114|PMID:10428842
Molecular Function	GO:0005515	protein binding	Esrrg	IPI	UniProtKB:Q9NS37	Mouse	MGI:MGI:4436999|PMID:19690166
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Esrrg	IDA		Mouse	MGI:MGI:5572884|PMID:15149736
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ESRRG	IDA		Human	PMID:28473536
Biological Process	GO:0006351	DNA-templated transcription	esrrga	IDA		Zfish	PMID:15088146
Biological Process	GO:0071599	otic vesicle development	esrrga	IMP	ZFIN:ZDB-MRPHLNO-141002-3	Zfish	PMID:24744145
Biological Process	GO:0071599	otic vesicle development	esrrga	IMP	ZFIN:ZDB-MRPHLNO-141002-2	Zfish	PMID:24744145
Biological Process	GO:0071599	otic vesicle development	esrrgb	IMP	ZFIN:ZDB-MRPHLNO-141002-5	Zfish	PMID:24744145
Biological Process	GO:0071599	otic vesicle development	esrrgb	IMP	ZFIN:ZDB-MRPHLNO-141002-4	Zfish	PMID:24744145
Biological Process	GO:0032475	otolith formation	esrrgb	IMP	ZFIN:ZDB-MRPHLNO-141002-5	Zfish	PMID:24744145
Biological Process	GO:0032475	otolith formation	esrrgb	IMP	ZFIN:ZDB-MRPHLNO-141002-4	Zfish	PMID:24744145
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	Esrrg	IMP		Mouse	MGI:MGI:3702375|PMID:17229846
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Esrrg	IDA		Mouse	MGI:MGI:3690144|PMID:12715898
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Esrrg	IDA		Mouse	MGI:MGI:1342114|PMID:10428842
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Esrrg	IMP		Mouse	MGI:MGI:5572884|PMID:15149736
Biological Process	GO:0006355	regulation of DNA-templated transcription	ESRRG	IDA		Human	PMID:23836911

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern