Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EI24
  • Mouse genes Ei24
  • Rat genes Ei24
  • Zfish genes ei24
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ei24

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0061676	importin-alpha family protein binding	EI24	IPI	UniProtKB:P52292	Human	PMID:24821838
Molecular Function	GO:0005515	protein binding	EI24	IPI	UniProtKB:O15173	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EI24	IPI	UniProtKB:Q12982	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EI24	IPI	UniProtKB:Q6PL24	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EI24	IPI	UniProtKB:Q9NUH8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EI24	IPI	UniProtKB:Q9UI14	Human	PMID:32296183
Cellular Component	GO:0005829	cytosol	EI24	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005783	endoplasmic reticulum	EI24	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005794	Golgi apparatus	EI24	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	EI24	HDA		Human	PMID:19946888
Biological Process	GO:0006914	autophagy	Ei24	IMP	MGI:MGI:2176173,MGI:MGI:5475023	Mouse	PMID:23074225
Biological Process	GO:0071494	cellular response to UV-C	Ei24	IGI	MGI:MGI:98834	Mouse	PMID:24014029
Biological Process	GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage	Ei24	IDA		Mouse	PMID:10594026
Biological Process	GO:0030308	negative regulation of cell growth	EI24	IDA		Human	PMID:10594026
Biological Process	GO:0042308	negative regulation of protein import into nucleus	Ei24	IDA		Mouse	PMID:24821838
Biological Process	GO:0050885	neuromuscular process controlling balance	Ei24	IMP	MGI:MGI:2176173,MGI:MGI:5475023	Mouse	PMID:23074225
Biological Process	GO:2001244	positive regulation of intrinsic apoptotic signaling pathway	Ei24	IMP		Mouse	PMID:17981155
Biological Process	GO:0009410	response to xenobiotic stimulus	Ei24	IMP		Mouse	PMID:17981155

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern