Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes E2F5
  • Mouse genes E2f5
  • Rat genes E2f5
  • Zfish genes e2f5
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set E2f5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001216	DNA-binding transcription activator activity	E2F5	IDA		Human	PMID:17062573
Molecular Function	GO:0003700	DNA-binding transcription factor activity	E2f5	IDA		Mouse	PMID:11591818
Molecular Function	GO:0003700	DNA-binding transcription factor activity	e2f5	IDA		Zfish	PMID:32196499
Molecular Function	GO:0005515	protein binding	E2F5	IPI	UniProtKB:P06400	Human	PMID:12502741
Molecular Function	GO:0005515	protein binding	E2F5	IPI	UniProtKB:P06400	Human	PMID:16360038
Molecular Function	GO:0005515	protein binding	E2F5	IPI	UniProtKB:Q14186	Human	PMID:16360038
Molecular Function	GO:0005515	protein binding	E2F5	IPI	UniProtKB:Q5H9I0	Human	PMID:17062573
Molecular Function	GO:0005515	protein binding	E2f5	IPI	UniProtKB:Q64163-4	Mouse	MGI:MGI:5508255|PMID:16482218
Molecular Function	GO:0005515	protein binding	E2f5	IPI	PR:Q08639	Mouse	PMID:15448153
Molecular Function	GO:0005515	protein binding	E2f5	IPI	RGD:3540	Rat	PMID:12063292|RGD:625751
Molecular Function	GO:0043565	sequence-specific DNA binding	E2f5	IDA		Rat	PMID:12063292|RGD:625751
Cellular Component	GO:0005737	cytoplasm	E2f5	IDA		Mouse	PMID:16172982
Cellular Component	GO:0001650	fibrillar center	E2F5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	E2F5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005730	nucleolus	E2F5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	E2F5	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	E2f5	IDA		Mouse	PMID:16172982
Cellular Component	GO:0005634	nucleus	E2f5	IDA		Rat	PMID:10725332|RGD:1581722
Cellular Component	GO:0016528	sarcoplasm	E2f5	IDA		Rat	PMID:10725332|RGD:1581722
Biological Process	GO:0009887	animal organ morphogenesis	E2f5	IMP	MGI:MGI:1926192	Mouse	PMID:9553039
Biological Process	GO:0019101	female somatic sex determination	e2f5	IMP	ZFIN:ZDB-GENO-210422-1	Zfish	PMID:32196499
Biological Process	GO:0007141	male meiosis I	e2f5	IMP	ZFIN:ZDB-GENO-210422-1	Zfish	PMID:32196499
Biological Process	GO:1903251	multi-ciliated epithelial cell differentiation	e2f5	IMP	ZFIN:ZDB-GENO-210422-1	Zfish	PMID:32196499
Biological Process	GO:0006355	regulation of DNA-templated transcription	E2f5	IDA		Mouse	PMID:11591818

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern