Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DYNC2I2
  • Mouse genes Dync2i2
  • Rat genes Dync2i2
  • Zfish genes dync2i2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dync2i2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045503	dynein light chain binding	DYNC2I2	IPI	UniProtKB:Q8WW35	Human	PMID:25830415
Molecular Function	GO:0005515	protein binding	DYNC2I2	IPI	UniProtKB:P38432	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DYNC2I2	IPI	UniProtKB:Q9BYV2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DYNC2I2	IPI	UniProtKB:Q96FJ2	Human	PMID:30649997
Molecular Function	GO:0005515	protein binding	DYNC2I2	IPI	UniProtKB:Q9NP97	Human	PMID:30649997
Molecular Function	GO:0005515	protein binding	DYNC2I2	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Dync2i2	IPI	PR:Q9D0M5	Mouse	PMID:25294941
Molecular Function	GO:0005515	protein binding	Dync2i2	IPI	PR:P63168	Mouse	PMID:25294941
Cellular Component	GO:0005930	axoneme	Dync2i2	IDA		Mouse	MGI:MGI:5551675|PMID:24183451
Cellular Component	GO:0005814	centriole	Dync2i2	IDA		Mouse	MGI:MGI:5551675|PMID:24183451
Cellular Component	GO:0005813	centrosome	DYNC2I2	IDA		Human	PMID:25205765
Cellular Component	GO:0036064	ciliary basal body	DYNC2I2	IDA		Human	PMID:25205765
Cellular Component	GO:0036064	ciliary basal body	Dync2i2	IDA		Mouse	MGI:MGI:5551675|PMID:24183451
Cellular Component	GO:0005929	cilium	DYNC2I2	IDA		Human	PMID:25205765
Cellular Component	GO:0005929	cilium	Dync2i2	IMP		Mouse	MGI:MGI:5906938|PMID:28379358
Cellular Component	GO:0005929	cilium	dync2i2	IMP	ZFIN:ZDB-MRPHLNO-100217-25	Zfish	PMID:19474410|ZFIN:ZDB-PUB-090601-13
Cellular Component	GO:0005737	cytoplasm	DYNC2I2	IDA		Human	PMID:25205765
Cellular Component	GO:0005868	cytoplasmic dynein complex	DYNC2I2	IDA		Human	PMID:25205765
Cellular Component	GO:0005868	cytoplasmic dynein complex	DYNC2I2	IDA		Human	PMID:25830415
Cellular Component	GO:0005868	cytoplasmic dynein complex	DYNC2I2	IDA		Human	PMID:31451806
Cellular Component	GO:0005868	cytoplasmic dynein complex	Dync2i2	IPI	PR:Q9D0M5	Mouse	PMID:25294941
Cellular Component	GO:0005868	cytoplasmic dynein complex	Dync2i2	IPI	PR:P63168	Mouse	PMID:25294941
Cellular Component	GO:0005829	cytosol	DYNC2I2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0030175	filopodium	Dync2i2	IMP		Mouse	MGI:MGI:5906938|PMID:28379358
Biological Process	GO:0060271	cilium assembly	DYNC2I2	IGI	UniProtKB:Q8WVS4	Human	PMID:25205765
Biological Process	GO:0060271	cilium assembly	Dync2i2	IDA		Mouse	MGI:MGI:5906938|PMID:28379358
Biological Process	GO:0035721	intraciliary retrograde transport	DYNC2I2	IMP		Human	PMID:29742051
Biological Process	GO:0035721	intraciliary retrograde transport	DYNC2I2	IMP		Human	PMID:30649997
Biological Process	GO:0035721	intraciliary retrograde transport	Dync2i2	IMP		Mouse	MGI:MGI:5906938|PMID:28379358
Biological Process	GO:0042073	intraciliary transport	dync2i2	IMP	ZFIN:ZDB-MRPHLNO-100217-25	Zfish	PMID:19474410
Biological Process	GO:0021915	neural tube development	dync2i2	IMP	ZFIN:ZDB-MRPHLNO-100217-25	Zfish	PMID:32576942

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern