About   Help   FAQ
Wdr34 Gene Detail
Summary
  • Symbol
    Wdr34
  • Name
    WD repeat domain 34
  • Synonyms
    3200002I06Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919070
    NCBI Gene: 71820
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr2:30031551-30048879 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 21.04 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    49 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919070
protein coding gene Chr2:30031546-30048881 (-)
129S1/SvImJ MGP_129S1SvImJ_G0025550
protein coding gene Chr2:28225436-28242738 (-)
A/J MGP_AJ_G0025528
protein coding gene Chr2:27106467-27123756 (-)
AKR/J MGP_AKRJ_G0025497
protein coding gene Chr2:28028981-28046298 (-)
BALB/cJ MGP_BALBcJ_G0025523
protein coding gene Chr2:27236836-27254927 (-)
C3H/HeJ MGP_C3HHeJ_G0025285
protein coding gene Chr2:27955599-27972920 (-)
C57BL/6NJ MGP_C57BL6NJ_G0025968
protein coding gene Chr2:29131496-29151697 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0023377
protein coding gene Chr2:25901948-25919982 (-)
CAST/EiJ MGP_CASTEiJ_G0024748
protein coding gene Chr2:27840494-27857628 (-)
CBA/J MGP_CBAJ_G0025262
protein coding gene Chr2:30133974-30159656 (-)
DBA/2J MGP_DBA2J_G0025395
protein coding gene Chr2:26901460-26918795 (-)
FVB/NJ MGP_FVBNJ_G0025358
protein coding gene Chr2:26707840-26726763 (-)
LP/J MGP_LPJ_G0025481
protein coding gene Chr2:28139801-28159210 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0025388
protein coding gene Chr2:30057554-30077564 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0026027
protein coding gene Chr2:27950126-27968479 (-)
PWK/PhJ MGP_PWKPhJ_G0024494
protein coding gene Chr2:26731979-26750060 (-)
SPRET/EiJ MGP_SPRETEiJ_G0024294
protein coding gene Chr2:28022996-28042019 (-)
WSB/EiJ MGP_WSBEiJ_G0024816
protein coding gene Chr2:28063068-28080516 (-)



Homology
more
  • Human Ortholog
    WDR34, WD repeat domain 34
  • Vertebrate Orthologs
    10
  • Human Ortholog
    WDR34, WD repeat domain 34
    Orthology source: HomoloGene, HGNC
  • Synonyms
    bA216B9.3, DIC5, FAP133, SRTD11
  • Links
    NCBI Gene ID: 89891
    neXtProt AC: NX_Q96EX3
    UniProt: Q96EX3

  • Chr Location
    9q34.11; chr9:128633653-128656850 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 14156
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: WDR34
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human WDR34 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 71820 NCBI Gene Model | MGI Sequence Detail 17329 C57BL/6J ±  kb
transcript NM_001008498 RefSeq | MGI Sequence Detail 1812 C57BL/6  
polypeptide Q5U4F6 UniProt | EBI | MGI Sequence Detail 535 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    2 Sequences
  • InterPro Domains
    IPR001680 WD40 repeat
    IPR017986 WD40-repeat-containing domain
    IPR036322 WD40-repeat-containing domain superfamily
    IPR015943 WD40/YVTN repeat-like-containing domain superfamily
Molecular
Reagents
less
  • All nucleic 28
    cDNA 28

    Microarray probesets 3
References
more
  • Summaries
    All 28
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:242833 Wu C, et al., Loss of dynein-2 intermediate chain Wdr34 results in defects in retrograde ciliary protein trafficking and Hedgehog signaling in the mouse. Hum Mol Genet. 2017 Jul 01;26(13):2386-2397

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
03/19/2019
MGI 6.13
The Jackson Laboratory