Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DYNC1LI1
  • Mouse genes Dync1li1
  • Rat genes Dync1li1
  • Zfish genes dync1li1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dync1li1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045504	dynein heavy chain binding	DYNC1LI1	IPI	UniProtKB:Q14204	Human	PMID:25272277
Molecular Function	GO:0019003	GDP binding	DYNC1LI1	IDA		Human	PMID:25272277
Molecular Function	GO:0042802	identical protein binding	Dync1li1	IPI	RGD:71072	Rat	PMID:10893222|RGD:632618
Molecular Function	GO:0060090	molecular adaptor activity	DYNC1LI1	EXP		Human	PMID:30615611
Molecular Function	GO:0005515	protein binding	DYNC1LI1	IPI	UniProtKB:O75154	Human	PMID:25272277
Molecular Function	GO:0005515	protein binding	DYNC1LI1	IPI	UniProtKB:Q921C5	Human	PMID:25272277
Molecular Function	GO:0005515	protein binding	DYNC1LI1	IPI	UniProtKB:Q96NA2	Human	PMID:25272277
Molecular Function	GO:0005515	protein binding	DYNC1LI1	IPI	UniProtKB:Q04864	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	DYNC1LI1	IPI	UniProtKB:Q86VS8	Human	PMID:27482052
Molecular Function	GO:0005515	protein binding	DYNC1LI1	IPI	UniProtKB:O75154,UniProtKB:Q86VS8,UniProtKB:Q8TD16,UniProtKB:Q96EA4,UniProtKB:Q96NA2	Human	PMID:30615611
Molecular Function	GO:0005515	protein binding	DYNC1LI1	IPI	UniProtKB:Q8TD16,UniProtKB:Q96EA4	Human	PMID:30615611
Molecular Function	GO:0005515	protein binding	DYNC1LI1	IPI	UniProtKB:Q96EA4	Human	PMID:30615611
Molecular Function	GO:0005515	protein binding	DYNC1LI1	IPI	UniProtKB:Q04864	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	DYNC1LI1	IPI	UniProtKB:P15259	Human	PMID:32296183
Molecular Function	GO:0003723	RNA binding	DYNC1LI1	HDA		Human	PMID:22658674
Cellular Component	GO:0005813	centrosome	DYNC1LI1	IDA		Human	PMID:21399614
Cellular Component	GO:0005813	centrosome	Dync1li1	IDA		Rat	PMID:21169557|RGD:13207422
Cellular Component	GO:0005868	cytoplasmic dynein complex	DYNC1LI1	IDA		Human	PMID:19229290
Cellular Component	GO:0005868	cytoplasmic dynein complex	DYNC1LI1	IDA		Human	PMID:25272277
Cellular Component	GO:0000776	kinetochore	DYNC1LI1	IDA		Human	PMID:19229290
Cellular Component	GO:0000776	kinetochore	Dync1li1	IDA		Rat	PMID:21169557|RGD:13207422
Cellular Component	GO:0005770	late endosome	Dync1li1	IDA		Rat	PMID:21169557|RGD:13207422
Cellular Component	GO:0005764	lysosome	Dync1li1	IDA		Rat	PMID:21169557|RGD:13207422
Cellular Component	GO:0016020	membrane	DYNC1LI1	HDA		Human	PMID:19946888
Cellular Component	GO:0000922	spindle pole	DYNC1LI1	IDA		Human	PMID:19229290
Biological Process	GO:1990090	cellular response to nerve growth factor stimulus	Dync1li1	IDA		Rat	PMID:11536324|RGD:13207410
Biological Process	GO:0090267	positive regulation of mitotic cell cycle spindle assembly checkpoint	DYNC1LI1	IMP		Human	PMID:19229290
Biological Process	GO:0046605	regulation of centrosome cycle	Dync1li1	IDA		Rat	PMID:10545494|RGD:70723
Biological Process	GO:0009794	regulation of mitotic cell cycle, embryonic	dync1li1	IMP	ZFIN:ZDB-MRPHLNO-170201-3	Zfish	PMID:28003657
Biological Process	GO:0060236	regulation of mitotic spindle organization	dync1li1	IMP	ZFIN:ZDB-MRPHLNO-170201-3	Zfish	PMID:28003657

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern