Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DTX1
  • Mouse genes Dtx1
  • Rat genes Dtx1
  • Zfish genes dtx1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dtx1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005112	Notch binding	DTX1	IDA		Human	PMID:11564735
Molecular Function	GO:0005515	protein binding	DTX1	IPI	UniProtKB:P0CG48	Human	PMID:17028573
Molecular Function	GO:0005515	protein binding	DTX1	IPI	UniProtKB:P46108	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	DTX1	IPI	UniProtKB:Q9DCH4	Human	PMID:21124883
Molecular Function	GO:0005515	protein binding	DTX1	IPI	UniProtKB:P10644	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DTX1	IPI	UniProtKB:P46108	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	DTX1	IPI	UniProtKB:Q99466	Human	PMID:7671825
Molecular Function	GO:0005515	protein binding	Dtx1	IPI	PR:Q01705	Mouse	PMID:11226752
Molecular Function	GO:0031625	ubiquitin protein ligase binding	DTX1	IPI	UniProtKB:Q96J02	Human	PMID:17028573
Cellular Component	GO:0005829	cytosol	DTX1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016604	nuclear body	DTX1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	DTX1	IDA		Human	GO_REF:0000052
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	Dtx1	IEP		Mouse	PMID:20439489
Biological Process	GO:0010001	glial cell differentiation	Dtx1	IMP		Mouse	PMID:15965470
Biological Process	GO:0010001	glial cell differentiation	dtx1	IMP	ZFIN:ZDB-MRPHLNO-130503-1	Zfish	PMID:26714454
Biological Process	GO:0010001	glial cell differentiation	dtx1	IGI	ZFIN:ZDB-GENE-130502-1,ZFIN:ZDB-MRPHLNO-130503-1,ZFIN:ZDB-MRPHLNO-130503-2	Zfish	PMID:23328254
Biological Process	GO:0045665	negative regulation of neuron differentiation	DTX1	IGI	UniProtKB:Q01705	Human	PMID:11564735
Biological Process	GO:0045581	negative regulation of T cell differentiation	Dtx1	IDA		Mouse	PMID:12794108
Biological Process	GO:0022008	neurogenesis	dtx1	IGI	ZFIN:ZDB-GENE-130502-1,ZFIN:ZDB-MRPHLNO-130503-1,ZFIN:ZDB-MRPHLNO-130503-2	Zfish	PMID:23328254
Biological Process	GO:0030182	neuron differentiation	dtx1	IMP	ZFIN:ZDB-MRPHLNO-130503-1	Zfish	PMID:26714454
Biological Process	GO:0007219	Notch signaling pathway	Dtx1	IMP		Mouse	PMID:15965470
Biological Process	GO:0007219	Notch signaling pathway	Dtx1	IDA		Mouse	PMID:11226752
Biological Process	GO:0007219	Notch signaling pathway	dtx1	IMP	ZFIN:ZDB-MRPHLNO-130503-1	Zfish	PMID:26714454
Biological Process	GO:0008593	regulation of Notch signaling pathway	DTX1	IGI	UniProtKB:Q01705	Human	PMID:11564735
Biological Process	GO:0030217	T cell differentiation	Dtx1	IDA		Mouse	PMID:12794108

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern