Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DPYSL3
  • Mouse genes Dpysl3
  • Rat genes Dpysl3
  • Zfish genes dpysl3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dpysl3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0035374	chondroitin sulfate binding	Dpysl3	IDA		Rat	PMID:12444086|RGD:1298811
Molecular Function	GO:0031005	filamin binding	DPYSL3	IPI	UniProtKB:P21333	Human	PMID:25358863
Molecular Function	GO:0042802	identical protein binding	Dpysl3	IPI	UniProtKB:Q62952	Rat	PMID:16181627|RGD:8553533
Molecular Function	GO:0051219	phosphoprotein binding	Dpysl3	IPI	UniProtKB:Q9DDZ6	Mouse	MGI:MGI:1927681|PMID:10956643
Molecular Function	GO:0005515	protein binding	DPYSL3	IPI	UniProtKB:Q96AP0	Human	PMID:21044950
Molecular Function	GO:0005515	protein binding	DPYSL3	IPI	UniProtKB:Q16555	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	DPYSL3	IPI	UniProtKB:Q16555	Human	PMID:29892012
Molecular Function	GO:0005515	protein binding	DPYSL3	IPI	UniProtKB:Q16555	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	Dpysl3	IPI	PR:Q61626	Mouse	PMID:24227739
Molecular Function	GO:0017124	SH3 domain binding	Dpysl3	IDA		Rat	PMID:12684468|RGD:1298810
Cellular Component	GO:0044297	cell body	Dpysl3	IDA		Rat	PMID:16181627|RGD:8553533
Cellular Component	GO:0005829	cytosol	Dpysl3	IDA		Rat	PMID:16181627|RGD:8553533
Cellular Component	GO:0070382	exocytic vesicle	Dpysl3	IDA		Rat	PMID:12684468|RGD:1298810
Cellular Component	GO:0005615	extracellular space	Dpysl3	IDA		Rat	PMID:12444086|RGD:1298811
Cellular Component	GO:0031941	filamentous actin	Dpysl3	IDA		Rat	PMID:16181627|RGD:8553533
Cellular Component	GO:0030426	growth cone	Dpysl3	IDA		Rat	PMID:12684468|RGD:1298810
Cellular Component	GO:0030426	growth cone	Dpysl3	IDA		Rat	PMID:17301178|RGD:8554848
Cellular Component	GO:0030027	lamellipodium	Dpysl3	IDA		Rat	PMID:16181627|RGD:8553533
Cellular Component	GO:0045202	synapse	Dpysl3	EXP		Rat	PMID:15169875|RGD:13702216
Cellular Component	GO:0045202	synapse	Dpysl3	IDA		Rat	PMID:15169875|RGD:13702216
Biological Process	GO:0051764	actin crosslink formation	Dpysl3	IDA		Rat	PMID:16181627|RGD:8553533
Biological Process	GO:0051017	actin filament bundle assembly	Dpysl3	IDA		Rat	PMID:16181627|RGD:8553533
Biological Process	GO:0007411	axon guidance	dpysl3	IMP	ZFIN:ZDB-MRPHLNO-110107-1	Zfish	PMID:30034463
Biological Process	GO:0007411	axon guidance	dpysl3	IGI	ZFIN:ZDB-MRPHLNO-050906-3,ZFIN:ZDB-MRPHLNO-110107-1	Zfish	PMID:30034463
Biological Process	GO:0007409	axonogenesis	dpysl3	IGI	ZFIN:ZDB-MRPHLNO-110107-1,ZFIN:ZDB-MRPHLNO-121029-1	Zfish	PMID:30034463
Biological Process	GO:0071345	cellular response to cytokine stimulus	Dpysl3	IEP		Rat	PMID:20800647|RGD:8554592
Biological Process	GO:0030336	negative regulation of cell migration	Dpysl3	IMP		Rat	PMID:16181627|RGD:8553533
Biological Process	GO:0010977	negative regulation of neuron projection development	Dpysl3	IMP		Rat	PMID:17301178|RGD:8554848
Biological Process	GO:0007399	nervous system development	Dpysl3	IDA		Mouse	PMID:12687705
Biological Process	GO:0048666	neuron development	Dpysl3	IEP		Rat	PMID:8815901|RGD:1298809
Biological Process	GO:0048936	peripheral nervous system neuron axonogenesis	dpysl3	IGI	ZFIN:ZDB-MRPHLNO-051128-3,ZFIN:ZDB-MRPHLNO-110107-1	Zfish	PMID:21108318
Biological Process	GO:0048936	peripheral nervous system neuron axonogenesis	dpysl3	IMP		Zfish	PMID:21108318
Biological Process	GO:0051491	positive regulation of filopodium assembly	Dpysl3	IDA		Rat	PMID:17301178|RGD:8554848
Biological Process	GO:0010976	positive regulation of neuron projection development	Dpysl3	IDA		Rat	PMID:12684468|RGD:1298810
Biological Process	GO:0048678	response to axon injury	Dpysl3	IEP		Rat	PMID:20800647|RGD:8554592

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern