Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DOCK7
  • Mouse genes Dock7
  • Rat genes Dock7
  • Zfish genes dock7
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dock7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	DOCK7	IPI	UniProtKB:O75427	Human	PMID:24255178
Molecular Function	GO:0005515	protein binding	DOCK7	IPI	UniProtKB:Q9HC29	Human	PMID:27812135
Molecular Function	GO:0005515	protein binding	DOCK7	IPI	UniProtKB:O15027	Human	PMID:29187380
Molecular Function	GO:0005515	protein binding	DOCK7	IPI	UniProtKB:Q6ZNJ1	Human	PMID:29187380
Molecular Function	GO:0005515	protein binding	DOCK7	IPI	UniProtKB:O75427	Human	PMID:32203420
Molecular Function	GO:0005515	protein binding	Dock7	IPI	UniProtKB:P97784	Mouse	MGI:MGI:5009503|PMID:19129230
Molecular Function	GO:0005515	protein binding	Dock7	IPI	UniProtKB:Q9JJ11	Mouse	MGI:MGI:5447899|PMID:22842144
Molecular Function	GO:0031267	small GTPase binding	DOCK7	IDA		Human	PMID:16982419
Molecular Function	GO:0031267	small GTPase binding	Dock7	IDA		Mouse	MGI:MGI:3687387|PMID:16982419
Cellular Component	GO:0005925	focal adhesion	DOCK7	HDA		Human	PMID:21423176
Cellular Component	GO:0031594	neuromuscular junction	Dock7	IMP		Mouse	PMID:21041412
Cellular Component	GO:0031594	neuromuscular junction	Dock7	IDA		Mouse	PMID:21041412
Biological Process	GO:0090630	activation of GTPase activity	DOCK7	IDA		Human	PMID:16982419
Biological Process	GO:0007409	axonogenesis	DOCK7	IMP		Human	PMID:16982419
Biological Process	GO:0045200	establishment of neuroblast polarity	DOCK7	IMP		Human	PMID:16982419
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	Dock7	IGI	MGI:MGI:1343184	Mouse	PMID:24029230
Biological Process	GO:0022027	interkinetic nuclear migration	Dock7	IMP		Mouse	MGI:MGI:5447899|PMID:22842144
Biological Process	GO:0000226	microtubule cytoskeleton organization	DOCK7	IMP		Human	PMID:16982419
Biological Process	GO:0120163	negative regulation of cold-induced thermogenesis	Dock7	IMP		Mouse	MGI:MGI:5912681|PMID:23553822
Biological Process	GO:0031175	neuron projection development	DOCK7	IMP		Human	PMID:16982419
Biological Process	GO:0043473	pigmentation	Dock7	IMP	MGI:MGI:1856946	Mouse	PMID:2379821
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	DOCK7	IMP		Human	PMID:16982419
Biological Process	GO:1904754	positive regulation of vascular associated smooth muscle cell migration	DOCK7	IMP		Human	PMID:22158624
Biological Process	GO:0098698	postsynaptic specialization assembly	Dock7	IDA		Mouse	PMID:21041412
Biological Process	GO:0098698	postsynaptic specialization assembly	Dock7	IMP		Mouse	PMID:21041412
Biological Process	GO:0050767	regulation of neurogenesis	Dock7	IMP		Mouse	MGI:MGI:5447899|PMID:22842144

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern