Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DLX4
  • Mouse genes Dlx4
  • Rat genes Dlx4
  • Zfish genes dlx4a,dlx4b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dlx4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	DLX4	IDA		Human	PMID:11909945
Molecular Function	GO:0005515	protein binding	DLX4	IPI	UniProtKB:P16333	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	DLX4	IPI	UniProtKB:P08047	Human	PMID:21297662
Molecular Function	GO:0005515	protein binding	DLX4	IPI	UniProtKB:Q13485	Human	PMID:21297662
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	DLX4	IDA		Human	PMID:11909945
Molecular Function	GO:0043565	sequence-specific DNA binding	DLX4	IDA		Human	PMID:9073066
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	DLX4	IDA		Human	PMID:28473536
Cellular Component	GO:0005654	nucleoplasm	DLX4	IDA		Human	GO_REF:0000052
Biological Process	GO:0042667	auditory receptor cell fate specification	dlx4b	IGI	ZFIN:ZDB-MRPHLNO-041109-1,ZFIN:ZDB-MRPHLNO-041110-1	Zfish	PMID:23571216
Biological Process	GO:0043010	camera-type eye development	dlx4b	IGI	ZFIN:ZDB-MRPHLNO-041109-1,ZFIN:ZDB-MRPHLNO-041110-1	Zfish	PMID:15728669
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	dlx4b	IGI	ZFIN:ZDB-MRPHLNO-041109-1,ZFIN:ZDB-MRPHLNO-050209-12,ZFIN:ZDB-MRPHLNO-060822-7	Zfish	PMID:20573696
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	dlx4b	IGI	ZFIN:ZDB-GENO-100809-9,ZFIN:ZDB-MRPHLNO-041109-1,ZFIN:ZDB-MRPHLNO-050209-12,ZFIN:ZDB-MRPHLNO-060822-7	Zfish	PMID:20573696
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	dlx4b	IMP	ZFIN:ZDB-MRPHLNO-050209-10,ZFIN:ZDB-MRPHLNO-050209-12	Zfish	PMID:25954033
Biological Process	GO:0035270	endocrine system development	dlx4b	IGI	ZFIN:ZDB-MRPHLNO-041109-1,ZFIN:ZDB-MRPHLNO-041110-1	Zfish	PMID:15728669
Biological Process	GO:0060119	inner ear receptor cell development	dlx4b	IGI	ZFIN:ZDB-GENO-180223-3	Zfish	PMID:28751305
Biological Process	GO:0070306	lens fiber cell differentiation	dlx4b	IGI	ZFIN:ZDB-MRPHLNO-041109-1,ZFIN:ZDB-MRPHLNO-041110-1	Zfish	PMID:15728669
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	DLX4	IDA		Human	PMID:11909945
Biological Process	GO:0048666	neuron development	dlx4b	IGI	ZFIN:ZDB-MRPHLNO-050209-11,ZFIN:ZDB-MRPHLNO-050209-12	Zfish	PMID:15581883
Biological Process	GO:0048666	neuron development	dlx4b	IGI	ZFIN:ZDB-MRPHLNO-050209-10,ZFIN:ZDB-MRPHLNO-050209-9	Zfish	PMID:15581883
Biological Process	GO:0030910	olfactory placode formation	dlx4b	IGI	ZFIN:ZDB-MRPHLNO-050208-13,ZFIN:ZDB-MRPHLNO-070504-2	Zfish	PMID:12070088
Biological Process	GO:0030910	olfactory placode formation	dlx4b	IGI	ZFIN:ZDB-MRPHLNO-070504-1,ZFIN:ZDB-MRPHLNO-070504-3	Zfish	PMID:12070088
Biological Process	GO:0030910	olfactory placode formation	dlx4b	IGI	ZFIN:ZDB-MRPHLNO-070504-1,ZFIN:ZDB-MRPHLNO-070504-2	Zfish	PMID:12070088
Biological Process	GO:0030910	olfactory placode formation	dlx4b	IGI	ZFIN:ZDB-MRPHLNO-050208-13,ZFIN:ZDB-MRPHLNO-070504-3	Zfish	PMID:12070088
Biological Process	GO:0043049	otic placode formation	dlx4b	IGI	ZFIN:ZDB-MRPHLNO-050208-13,ZFIN:ZDB-MRPHLNO-070504-3	Zfish	PMID:12070088
Biological Process	GO:0043049	otic placode formation	dlx4b	IGI	ZFIN:ZDB-MRPHLNO-070504-1,ZFIN:ZDB-MRPHLNO-070504-2	Zfish	PMID:12070088
Biological Process	GO:0043049	otic placode formation	dlx4b	IGI	ZFIN:ZDB-GENE-980526-280	Zfish	PMID:15188428
Biological Process	GO:0043049	otic placode formation	dlx4b	IGI	ZFIN:ZDB-GENE-001103-1,ZFIN:ZDB-GENE-980526-280	Zfish	PMID:12668634
Biological Process	GO:0043049	otic placode formation	dlx4b	IGI	ZFIN:ZDB-MRPHLNO-070504-1,ZFIN:ZDB-MRPHLNO-070504-3	Zfish	PMID:12070088
Biological Process	GO:0043049	otic placode formation	dlx4b	IGI	ZFIN:ZDB-MRPHLNO-050208-13,ZFIN:ZDB-MRPHLNO-070504-2	Zfish	PMID:12070088
Biological Process	GO:0030916	otic vesicle formation	dlx4b	IGI	ZFIN:ZDB-GENE-980526-280,ZFIN:ZDB-GENO-030617-1	Zfish	PMID:15188428
Biological Process	GO:0071600	otic vesicle morphogenesis	dlx4b	IGI	ZFIN:ZDB-GENO-180223-3	Zfish	PMID:28751305
Biological Process	GO:0021559	trigeminal nerve development	dlx4b	IGI	ZFIN:ZDB-MRPHLNO-050209-11,ZFIN:ZDB-MRPHLNO-050209-12	Zfish	PMID:15581883
Biological Process	GO:0021559	trigeminal nerve development	dlx4b	IGI	ZFIN:ZDB-MRPHLNO-050209-10,ZFIN:ZDB-MRPHLNO-050209-9	Zfish	PMID:15581883

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern