Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DFFB
  • Mouse genes Dffb
  • Rat genes Dffb
  • Zfish genes dffb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dffb

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0097718	disordered domain specific binding	DFFB	IPI	UniProtKB:O00273	Human	PMID:11371636
Molecular Function	GO:0003677	DNA binding	Dffb	IDA		Mouse	PMID:15572351
Molecular Function	GO:0004536	DNA nuclease activity	DFFB	IMP		Human	PMID:19944011
Molecular Function	GO:0004536	DNA nuclease activity	Dffb	IDA		Rat	PMID:11425895|RGD:628524
Molecular Function	GO:0019899	enzyme binding	DFFB	IPI	UniProtKB:P11388	Human	PMID:10959840
Molecular Function	GO:0042802	identical protein binding	DFFB	IPI	UniProtKB:O76075	Human	PMID:11371636
Molecular Function	GO:0004518	nuclease activity	Dffb	IDA		Mouse	PMID:15572351
Molecular Function	GO:0005515	protein binding	DFFB	IPI	UniProtKB:O00273	Human	PMID:11371636
Molecular Function	GO:0005515	protein binding	DFFB	IPI	UniProtKB:O00273	Human	PMID:19882353
Molecular Function	GO:0005515	protein binding	DFFB	IPI	UniProtKB:O00273	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Dffb	IPI	UniProtKB:O00273|UniProtKB:O54786	Mouse	MGI:MGI:5508707|PMID:22727028
Molecular Function	GO:0005515	protein binding	Dffb	IPI	UniProtKB:Q9D1C8	Mouse	MGI:MGI:6294156|PMID:14557248
Molecular Function	GO:0005515	protein binding	Dffb	IPI	UniProtKB:O54786	Mouse	MGI:MGI:6294156|PMID:14557248
Molecular Function	GO:0005515	protein binding	Dffb	IPI	UniProtKB:O00273	Mouse	PMID:15572351
Molecular Function	GO:0005515	protein binding	Dffb	IPI	RGD:3192	Rat	PMID:15893727|RGD:1600871
Molecular Function	GO:0005515	protein binding	Dffb	IPI	UniProtKB:Q63369	Rat	PMID:16642037|RGD:8553551
Molecular Function	GO:0019904	protein domain specific binding	DFFB	IPI	UniProtKB:O00273	Human	PMID:19944011
Cellular Component	GO:0000785	chromatin	DFFB	IDA		Human	PMID:22253444
Cellular Component	GO:0000785	chromatin	DFFB	IDA		Human	PMID:19882353
Cellular Component	GO:0005829	cytosol	DFFB	IDA		Human	PMID:22253444
Cellular Component	GO:0005829	cytosol	DFFB	IDA		Human	PMID:9108473
Cellular Component	GO:0005730	nucleolus	DFFB	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	DFFB	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	DFFB	IDA		Human	PMID:10959840
Cellular Component	GO:0005634	nucleus	DFFB	IDA		Human	PMID:15572351
Cellular Component	GO:0005634	nucleus	DFFB	IDA		Human	PMID:22253444
Cellular Component	GO:0005634	nucleus	Dffb	IDA		Rat	PMID:11425895|RGD:628524
Cellular Component	GO:0032991	protein-containing complex	DFFB	IDA		Human	PMID:11371636
Biological Process	GO:0030263	apoptotic chromosome condensation	DFFB	IDA		Human	PMID:10959840
Biological Process	GO:0006309	apoptotic DNA fragmentation	DFFB	IDA		Human	PMID:15572351
Biological Process	GO:0006309	apoptotic DNA fragmentation	DFFB	IDA		Human	PMID:22253444
Biological Process	GO:0006309	apoptotic DNA fragmentation	Dffb	IDA		Rat	PMID:11425895|RGD:628524
Biological Process	GO:0007420	brain development	Dffb	IEP		Rat	PMID:11425895|RGD:628524
Biological Process	GO:0006308	DNA catabolic process	DFFB	IMP		Human	PMID:19944011
Biological Process	GO:1902511	negative regulation of apoptotic DNA fragmentation	DFFB	IDA		Human	PMID:11371636

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern