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Gene Ontology Browser
Term Detail
GO term:nuclease activity
GO id:GO:0004518
Definition:Catalysis of the hydrolysis of ester linkages within nucleic acids.
CommentsNote that 'tRNA nucleotidyltransferase activity ; GO:0009022', also known as 'ribonuclease PH', does not have parentage in the 'nuclease activity' branch of the ontology because both GO and the Enzyme Commission define nuclease activity as a type of hydrolysis.
Number of paths to term: 1

is-adenotes an 'is-a' relationship
part-ofdenotes a 'part-of' relationship
regulatesdenotes a 'regulates' relationship
positively-regulatesdenotes a 'positively-regulates' relationship
negatively-regulatesdenotes a 'negatively-regulates' relationship


Gene_Ontology
        is-amolecular_function
                is-acatalytic activity
                        is-ahydrolase activity
                                is-ahydrolase activity, acting on ester bonds
                                        is-aaspartyl esterase activity
                                        is-acarboxylic ester hydrolase activity +
                                        is-aenterochelin esterase activity
                                        is-alipase activity +
                                        is-anuclease activity [GO:0004518] (189 genes, 613 annotations)
                                                is-adeoxyribonuclease activity +
                                                is-aendonuclease activity +
                                                is-aexonuclease activity +
                                                is-aoligonucleotidase activity +
                                                is-aribonuclease activity +
                                        is-aphosphoric ester hydrolase activity +
                                        is-asulfuric ester hydrolase activity +
                                        is-athiolester hydrolase activity +


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/01/2014
MGI 5.18
The Jackson Laboratory