Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DDB2
  • Mouse genes Ddb2
  • Rat genes Ddb2
  • Zfish genes ddb2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ddb2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003684	damaged DNA binding	DDB2	IDA		Human	PMID:22334663
Molecular Function	GO:0005515	protein binding	DDB2	IPI	UniProtKB:Q16531	Human	PMID:12732143
Molecular Function	GO:0005515	protein binding	DDB2	IPI	UniProtKB:Q13619	Human	PMID:16473935
Molecular Function	GO:0005515	protein binding	DDB2	IPI	UniProtKB:Q16531	Human	PMID:16473935
Molecular Function	GO:0005515	protein binding	DDB2	IPI	UniProtKB:Q13619,UniProtKB:Q13620,UniProtKB:Q16531	Human	PMID:16949367
Molecular Function	GO:0005515	protein binding	DDB2	IPI	UniProtKB:Q16531	Human	PMID:16949367
Molecular Function	GO:0005515	protein binding	DDB2	IPI	UniProtKB:Q13619	Human	PMID:17041588
Molecular Function	GO:0005515	protein binding	DDB2	IPI	UniProtKB:Q16531	Human	PMID:17041588
Molecular Function	GO:0005515	protein binding	DDB2	IPI	UniProtKB:Q16531	Human	PMID:17360488
Molecular Function	GO:0005515	protein binding	DDB2	IPI	UniProtKB:Q16531	Human	PMID:19109893
Molecular Function	GO:0005515	protein binding	DDB2	IPI	UniProtKB:Q16531	Human	PMID:19966799
Molecular Function	GO:0005515	protein binding	DDB2	IPI	UniProtKB:Q13619	Human	PMID:21145461
Molecular Function	GO:0005515	protein binding	DDB2	IPI	UniProtKB:Q01831-1	Human	PMID:22039351
Molecular Function	GO:0005515	protein binding	DDB2	IPI	UniProtKB:Q16531	Human	PMID:22039351
Molecular Function	GO:0005515	protein binding	DDB2	IPI	UniProtKB:Q16531	Human	PMID:22822215
Molecular Function	GO:0005515	protein binding	DDB2	IPI	UniProtKB:Q13619	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	DDB2	IPI	UniProtKB:Q13619	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	DDB2	IPI	UniProtKB:Q16531	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	DDB2	IPI	UniProtKB:Q13619	Human	PMID:30945288
Molecular Function	GO:0005515	protein binding	DDB2	IPI	UniProtKB:P40337-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DDB2	IPI	UniProtKB:Q01094	Human	PMID:9418871
Molecular Function	GO:0005515	protein binding	DDB2	IPI	UniProtKB:Q16531	Human	PMID:9418871
Molecular Function	GO:0044877	protein-containing complex binding	DDB2	IPI	ComplexPortal:CPX-900	Human	PMID:11564863
Molecular Function	GO:0004842	ubiquitin-protein transferase activity	DDB2	IDA		Human	PMID:12732143
Cellular Component	GO:0030054	cell junction	DDB2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0080008	Cul4-RING E3 ubiquitin ligase complex	DDB2	IMP		Human	PMID:16949367
Cellular Component	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	DDB2	EXP		Human	PMID:22118460
Cellular Component	GO:0031464	Cul4A-RING E3 ubiquitin ligase complex	Ddb2	EXP		Mouse	MGI:MGI:6867266|PMID:22118460
Cellular Component	GO:0031465	Cul4B-RING E3 ubiquitin ligase complex	DDB2	IDA		Human	PMID:22334663
Cellular Component	GO:0005654	nucleoplasm	DDB2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	DDB2	IDA		Human	PMID:14751237
Cellular Component	GO:0032991	protein-containing complex	DDB2	IDA		Human	PMID:12732143
Cellular Component	GO:0090734	site of DNA damage	DDB2	IDA		Human	PMID:19109893
Biological Process	GO:0034644	cellular response to UV	DDB2	EXP		Human	PMID:22118460
Biological Process	GO:0034644	cellular response to UV	Ddb2	EXP		Mouse	MGI:MGI:6867266|PMID:22118460
Biological Process	GO:0006974	DNA damage response	DDB2	EXP		Human	PMID:22118460
Biological Process	GO:0006974	DNA damage response	Ddb2	EXP		Mouse	MGI:MGI:6867266|PMID:22118460
Biological Process	GO:0035518	histone H2A monoubiquitination	DDB2	IDA		Human	PMID:22334663
Biological Process	GO:0006289	nucleotide-excision repair	DDB2	IDA		Human	PMID:19109893
Biological Process	GO:0051865	protein autoubiquitination	DDB2	IDA		Human	PMID:12732143
Biological Process	GO:0000209	protein polyubiquitination	DDB2	IDA		Human	PMID:12732143
Biological Process	GO:0006290	pyrimidine dimer repair	Ddb2	IMP	MGI:MGI:3511965	Mouse	PMID:15558025
Biological Process	GO:0009411	response to UV	DDB2	IDA		Human	PMID:12732143
Biological Process	GO:0070914	UV-damage excision repair	DDB2	IDA		Human	PMID:14751237
Biological Process	GO:0070914	UV-damage excision repair	DDB2	IDA		Human	PMID:22334663

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern