Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DCN
  • Mouse genes Dcn
  • Rat genes Dcn
  • Zfish genes dcn
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dcn

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005518	collagen binding	Dcn	IDA		Rat	PMID:12840020|RGD:728372
Molecular Function	GO:0050840	extracellular matrix binding	Dcn	IDA		Mouse	PMID:18757743
Molecular Function	GO:0005539	glycosaminoglycan binding	Dcn	IDA		Mouse	PMID:18757743
Molecular Function	GO:0005515	protein binding	DCN	IPI	UniProtKB:O95388	Human	PMID:11598131
Molecular Function	GO:0005515	protein binding	DCN	IPI	UniProtKB:P02751	Human	PMID:1747115
Molecular Function	GO:0005515	protein binding	DCN	IPI	UniProtKB:P13497-2	Human	PMID:20026052
Molecular Function	GO:0005515	protein binding	DCN	IPI	UniProtKB:O75063	Human	PMID:25331875
Molecular Function	GO:0005515	protein binding	DCN	IPI	UniProtKB:O75063	Human	PMID:25789606
Molecular Function	GO:0005515	protein binding	dcn	IPI	UniProtKB:Q6P5M1	Zfish	PMID:20802085|ZFIN:ZDB-PUB-100910-6
Molecular Function	GO:0003723	RNA binding	DCN	HDA		Human	PMID:22658674
Cellular Component	GO:0005589	collagen type VI trimer	Dcn	IDA		Rat	PMID:12840020|RGD:728372
Cellular Component	GO:0062023	collagen-containing extracellular matrix	DCN	HDA		Human	PMID:20551380
Cellular Component	GO:0062023	collagen-containing extracellular matrix	DCN	HDA		Human	PMID:27559042
Cellular Component	GO:0062023	collagen-containing extracellular matrix	DCN	HDA		Human	PMID:28327460
Cellular Component	GO:0062023	collagen-containing extracellular matrix	DCN	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	DCN	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Dcn	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Dcn	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0031012	extracellular matrix	Dcn	IDA		Rat	PMID:12840020|RGD:728372
Cellular Component	GO:0005576	extracellular region	DCN	HDA		Human	PMID:27068509
Cellular Component	GO:0005615	extracellular space	DCN	HDA		Human	PMID:20551380
Biological Process	GO:0007568	aging	Dcn	IEP		Rat	PMID:14634004|RGD:2311426
Biological Process	GO:0051216	cartilage development	dcn	IMP	ZFIN:ZDB-MRPHLNO-090513-6	Zfish	PMID:19211552
Biological Process	GO:0050654	chondroitin sulfate proteoglycan metabolic process	dcn	IDA		Zfish	PMID:19211552
Biological Process	GO:0060028	convergent extension involved in axis elongation	dcn	IMP	ZFIN:ZDB-MRPHLNO-090513-6	Zfish	PMID:19211552
Biological Process	GO:0060028	convergent extension involved in axis elongation	dcn	IMP	ZFIN:ZDB-MRPHLNO-090513-5	Zfish	PMID:19211552
Biological Process	GO:0001822	kidney development	Dcn	IEP		Rat	PMID:15282150|RGD:1643132
Biological Process	GO:0016525	negative regulation of angiogenesis	DCN	IDA		Human	PMID:23978385
Biological Process	GO:0010596	negative regulation of endothelial cell migration	DCN	IDA		Human	PMID:23798385
Biological Process	GO:1900747	negative regulation of vascular endothelial growth factor signaling pathway	DCN	IDA		Human	PMID:23798385
Biological Process	GO:0019800	peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan	Dcn	IDA		Mouse	PMID:18757743
Biological Process	GO:0001890	placenta development	Dcn	IEP		Rat	PMID:16987756|RGD:2311421
Biological Process	GO:0010508	positive regulation of autophagy	DCN	IDA		Human	PMID:23798385
Biological Process	GO:0016239	positive regulation of macroautophagy	DCN	IDA		Human	PMID:23798385
Biological Process	GO:0016239	positive regulation of macroautophagy	DCN	IGI	UniProtKB:P35968	Human	PMID:23798385
Biological Process	GO:0051901	positive regulation of mitochondrial depolarization	DCN	IGI	UniProtKB:P35968	Human	PMID:23798385
Biological Process	GO:0090141	positive regulation of mitochondrial fission	DCN	IGI	UniProtKB:P35968	Human	PMID:23798385
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	DCN	IDA		Human	PMID:23798385
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	DCN	IGI	UniProtKB:Q3URU2	Human	PMID:23798385
Biological Process	GO:0032496	response to lipopolysaccharide	Dcn	IEP		Rat	PMID:18471238|RGD:2311419
Biological Process	GO:0009612	response to mechanical stimulus	Dcn	IEP		Rat	PMID:16525834|RGD:2311422
Biological Process	GO:0007519	skeletal muscle tissue development	Dcn	IEP		Rat	PMID:17679144|RGD:2303553
Biological Process	GO:0042060	wound healing	Dcn	IEP		Rat	PMID:19393425|RGD:2311417

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern