Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DACT3
  • Mouse genes Dact3
  • Rat genes Dact3
  • Zfish genes dact3a
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dact3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070097	delta-catenin binding	Dact3	IDA		Mouse	MGI:MGI:5437409|PMID:21718540
Molecular Function	GO:0042802	identical protein binding	Dact3	IPI	UniProtKB:Q0PHV7	Mouse	MGI:MGI:5437409|PMID:21718540
Molecular Function	GO:0005515	protein binding	Dact3	IPI	UniProtKB:Q7TN08|UniProtKB:Q8R4A3	Mouse	MGI:MGI:5437409|PMID:21718540
Molecular Function	GO:0051018	protein kinase A binding	Dact3	IDA		Mouse	MGI:MGI:5437409|PMID:21718540
Molecular Function	GO:0005080	protein kinase C binding	Dact3	IDA		Mouse	MGI:MGI:5437409|PMID:21718540
Cellular Component	GO:0005737	cytoplasm	Dact3	IDA		Mouse	PMID:23580654
Biological Process	GO:0060070	canonical Wnt signaling pathway	Dact3	IMP	MGI:MGI:5515616	Mouse	PMID:23580654
Biological Process	GO:0001837	epithelial to mesenchymal transition	Dact3	IMP	MGI:MGI:5515616	Mouse	PMID:23580654
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	DACT3	IDA		Human	PMID:18538736
Biological Process	GO:0090090	negative regulation of canonical Wnt signaling pathway	Dact3	IMP	MGI:MGI:5515616	Mouse	PMID:23580654
Biological Process	GO:0030308	negative regulation of cell growth	DACT3	IDA		Human	PMID:18538736
Biological Process	GO:0010719	negative regulation of epithelial to mesenchymal transition	Dact3	IMP	MGI:MGI:5515616	Mouse	PMID:23580654
Biological Process	GO:0030178	negative regulation of Wnt signaling pathway	DACT3	IDA		Human	PMID:18538736

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern