Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CYTH3
  • Mouse genes Cyth3
  • Rat genes Cyth3
  • Zfish genes cyth3a,cyth3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cyth3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	CYTH3	IDA		Human	PMID:23940353
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	CYTH3	IDA		Human	PMID:9707577
Molecular Function	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	CYTH3	IDA		Human	PMID:23940353
Molecular Function	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	CYTH3	IDA		Human	PMID:9742223
Molecular Function	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	Cyth3	IDA		Mouse	PMID:11001876
Molecular Function	GO:0005547	phosphatidylinositol-3,4,5-trisphosphate binding	Cyth3	IDA		Mouse	PMID:9072969
Molecular Function	GO:0005515	protein binding	CYTH3	IPI	UniProtKB:Q969H4	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	CYTH3	IPI	UniProtKB:Q8N0S2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CYTH3	IPI	UniProtKB:Q969H4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	CYTH3	IPI	UniProtKB:Q96HB5-4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Cyth3	IPI	PR:Q920B0	Mouse	PMID:11445584
Molecular Function	GO:0005515	protein binding	Cyth3	IPI	PR:Q9JJA9	Mouse	PMID:10828067
Cellular Component	GO:0005912	adherens junction	Cyth3	IDA		Mouse	MGI:MGI:4420836|PMID:20080746
Cellular Component	GO:0005923	bicellular tight junction	Cyth3	IDA		Mouse	MGI:MGI:4420836|PMID:20080746
Cellular Component	GO:0005737	cytoplasm	Cyth3	IDA		Mouse	PMID:11445584
Cellular Component	GO:0005829	cytosol	CYTH3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	CYTH3	IDA		Human	PMID:9742223
Cellular Component	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	CYTH3	IDA		Human	PMID:9742223
Cellular Component	GO:0005654	nucleoplasm	CYTH3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	CYTH3	IDA		Human	PMID:17398095
Cellular Component	GO:0005886	plasma membrane	Cyth3	IDA		Mouse	PMID:10605025
Cellular Component	GO:0001726	ruffle	Cyth3	IPI	UniProtKB:Q902B1	Mouse	PMID:11445584
Biological Process	GO:0055113	epiboly involved in gastrulation with mouth forming second	cyth3a	IGI	ZFIN:ZDB-GENE-030131-4311,ZFIN:ZDB-GENE-030131-657,ZFIN:ZDB-GENE-090624-6	Zfish	PMID:28736167
Biological Process	GO:0090162	establishment of epithelial cell polarity	Cyth3	IMP		Mouse	PMID:20080746
Biological Process	GO:0048193	Golgi vesicle transport	CYTH3	IMP		Human	PMID:9707577
Biological Process	GO:0045785	positive regulation of cell adhesion	Cyth3	IDA		Mouse	PMID:10605025

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern