Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CYTH1
  • Mouse genes Cyth1
  • Rat genes Cyth1
  • Zfish genes cyth1a,cyth1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cyth1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	CYTH1	IDA		Human	PMID:10652308
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	Cyth1	IDA		Mouse	MGI:MGI:5520046|PMID:18042453
Molecular Function	GO:0005515	protein binding	CYTH1	IPI	UniProtKB:O60759	Human	PMID:11867758
Molecular Function	GO:0005515	protein binding	CYTH1	IPI	UniProtKB:O60759	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CYTH1	IPI	UniProtKB:Q3KP66	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CYTH1	IPI	UniProtKB:Q969H4	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CYTH1	IPI	UniProtKB:Q96HB5	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	CYTH1	IPI	UniProtKB:Q3KP66	Human	PMID:29420262
Molecular Function	GO:0005515	protein binding	CYTH1	IPI	UniProtKB:O60759	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYTH1	IPI	UniProtKB:O75971-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYTH1	IPI	UniProtKB:P15408	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYTH1	IPI	UniProtKB:Q8WWN9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYTH1	IPI	UniProtKB:Q969H4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYTH1	IPI	UniProtKB:Q96HB5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	CYTH1	IPI	UniProtKB:P07900	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CYTH1	IPI	UniProtKB:P23560-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CYTH1	IPI	UniProtKB:P31749	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CYTH1	IPI	UniProtKB:P35520	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CYTH1	IPI	UniProtKB:Q92915-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CYTH1	IPI	UniProtKB:Q96BI3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CYTH1	IPI	UniProtKB:Q9NZ42	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	CYTH1	IPI	UniProtKB:Q9UNE7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Cyth1	IPI	PR:Q8BIE6	Mouse	PMID:20080746
Cellular Component	GO:0005923	bicellular tight junction	Cyth1	IDA		Mouse	PMID:20080746
Cellular Component	GO:0005737	cytoplasm	CYTH1	IDA		Human	PMID:12606567
Cellular Component	GO:0005829	cytosol	Cyth1	IDA		Mouse	MGI:MGI:5520046|PMID:18042453
Cellular Component	GO:0005829	cytosol	Cyth1	IDA		Mouse	MGI:MGI:6119883|PMID:29420262
Cellular Component	GO:0031234	extrinsic component of cytoplasmic side of plasma membrane	Cyth1	IDA		Mouse	MGI:MGI:5520046|PMID:18042453
Cellular Component	GO:0098888	extrinsic component of presynaptic membrane	Cyth1	IDA		Rat	PMID:9927699|RGD:13702340
Cellular Component	GO:0098888	extrinsic component of presynaptic membrane	Cyth1	IMP		Rat	PMID:9927699|RGD:13702340
Cellular Component	GO:0031594	neuromuscular junction	Cyth1	IDA		Rat	PMID:9927699|RGD:13702340
Cellular Component	GO:0031594	neuromuscular junction	Cyth1	IMP		Rat	PMID:9927699|RGD:13702340
Cellular Component	GO:0005886	plasma membrane	CYTH1	IDA		Human	PMID:12606567
Cellular Component	GO:0005886	plasma membrane	CYTH1	IDA		Human	PMID:17398095
Cellular Component	GO:0005886	plasma membrane	Cyth1	IDA		Mouse	MGI:MGI:6119883|PMID:29420262
Biological Process	GO:0055113	epiboly involved in gastrulation with mouth forming second	cyth1b	IGI	ZFIN:ZDB-GENE-030131-657,ZFIN:ZDB-GENE-090624-6,ZFIN:ZDB-GENE-120612-1	Zfish	PMID:28736167
Biological Process	GO:0055113	epiboly involved in gastrulation with mouth forming second	cyth1a	IGI	ZFIN:ZDB-GENE-030131-4311,ZFIN:ZDB-GENE-090624-6,ZFIN:ZDB-GENE-120612-1	Zfish	PMID:28736167
Biological Process	GO:0090162	establishment of epithelial cell polarity	Cyth1	IMP		Mouse	PMID:20080746
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Cyth1	IDA		Rat	PMID:9927699|RGD:13702340
Biological Process	GO:0099171	presynaptic modulation of chemical synaptic transmission	Cyth1	IMP		Rat	PMID:9927699|RGD:13702340
Biological Process	GO:0030155	regulation of cell adhesion	CYTH1	IDA		Human	PMID:12606567

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern