Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CUL7
  • Mouse genes Cul7
  • Rat genes Cul7
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Cul7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	CUL7	IPI	UniProtKB:P04637	Human	PMID:17298945
Molecular Function	GO:0005515	protein binding	CUL7	IPI	UniProtKB:O75147	Human	PMID:21572988
Molecular Function	GO:0005515	protein binding	CUL7	IPI	UniProtKB:O75147-2	Human	PMID:21572988
Molecular Function	GO:0005515	protein binding	CUL7	IPI	UniProtKB:Q86VX2	Human	PMID:21778237
Molecular Function	GO:0005515	protein binding	CUL7	IPI	UniProtKB:Q86X83	Human	PMID:21778237
Molecular Function	GO:0005515	protein binding	CUL7	IPI	UniProtKB:Q8N668	Human	PMID:21778237
Molecular Function	GO:0005515	protein binding	CUL7	IPI	UniProtKB:Q9GZQ3	Human	PMID:21778237
Molecular Function	GO:0005515	protein binding	CUL7	IPI	UniProtKB:Q9H0A8	Human	PMID:21778237
Molecular Function	GO:0005515	protein binding	CUL7	IPI	UniProtKB:Q9Y6G5	Human	PMID:21778237
Molecular Function	GO:0005515	protein binding	CUL7	IPI	UniProtKB:P04637	Human	PMID:22653443
Molecular Function	GO:0005515	protein binding	CUL7	IPI	UniProtKB:Q8IWT3	Human	PMID:24793696
Molecular Function	GO:0005515	protein binding	CUL7	IPI	UniProtKB:P04637	Human	PMID:25609649
Molecular Function	GO:0005515	protein binding	CUL7	IPI	UniProtKB:P04637	Human	PMID:34591612
Molecular Function	GO:0005515	protein binding	CUL7	IPI	UniProtKB:P04637	Human	PMID:35140242
Molecular Function	GO:0005515	protein binding	Cul7	IPI	UniProtKB:Q8BZM1	Mouse	MGI:MGI:2673022|PMID:12904573
Molecular Function	GO:0005515	protein binding	Cul7	IPI	PR:P62878	Mouse	PMID:16880526
Molecular Function	GO:0005515	protein binding	Cul7	IPI	PR:Q8BIA4	Mouse	PMID:16880526
Cellular Component	GO:1990393	3M complex	CUL7	IDA		Human	PMID:24793695
Cellular Component	GO:1990393	3M complex	CUL7	IDA		Human	PMID:24793696
Cellular Component	GO:0005813	centrosome	CUL7	IDA		Human	PMID:24793695
Cellular Component	GO:0031467	Cul7-RING ubiquitin ligase complex	CUL7	IDA		Human	PMID:18498745
Cellular Component	GO:0031467	Cul7-RING ubiquitin ligase complex	CUL7	IDA		Human	PMID:21572988
Cellular Component	GO:0031467	Cul7-RING ubiquitin ligase complex	CUL7	IDA		Human	PMID:24362026
Cellular Component	GO:0031467	Cul7-RING ubiquitin ligase complex	Cul7	IDA		Mouse	MGI:MGI:5493210|PMID:21572988
Cellular Component	GO:0005737	cytoplasm	CUL7	IDA		Human	PMID:24793695
Cellular Component	GO:0005794	Golgi apparatus	CUL7	IDA		Human	PMID:21572988
Cellular Component	GO:0005794	Golgi apparatus	Cul7	IDA		Rat	PMID:21572988|RGD:8554449
Cellular Component	GO:0048471	perinuclear region of cytoplasm	CUL7	IDA		Human	PMID:21572988
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Cul7	IDA		Rat	PMID:21572988|RGD:8554449
Biological Process	GO:0001837	epithelial to mesenchymal transition	CUL7	IDA		Human	PMID:20139075
Biological Process	GO:0007030	Golgi organization	Cul7	IMP		Rat	PMID:21572988|RGD:8554449
Biological Process	GO:0000226	microtubule cytoskeleton organization	CUL7	IMP		Human	PMID:24793695
Biological Process	GO:0000281	mitotic cytokinesis	CUL7	IMP		Human	PMID:24793695
Biological Process	GO:0001890	placenta development	CUL7	IDA		Human	PMID:20139075
Biological Process	GO:0050775	positive regulation of dendrite morphogenesis	CUL7	IGI	UniProtKB:D3ZEF4	Human	PMID:21572988
Biological Process	GO:0050775	positive regulation of dendrite morphogenesis	Cul7	IMP		Rat	PMID:21572988|RGD:8554449
Biological Process	GO:0016567	protein ubiquitination	CUL7	IDA		Human	PMID:18498745
Biological Process	GO:0007088	regulation of mitotic nuclear division	CUL7	IMP		Human	PMID:24793695
Biological Process	GO:0001570	vasculogenesis	Cul7	IMP		Mouse	MGI:MGI:2673022|PMID:12904573

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern