Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes CSF3
  • Mouse genes Csf3
  • Rat genes Csf3
  • Zfish genes csf3a,csf3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Csf3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005125	cytokine activity	CSF3	IDA		Human	PMID:23001182
Molecular Function	GO:0019899	enzyme binding	CSF3	IPI	UniProtKB:P08246	Human	PMID:12393522
Molecular Function	GO:0005130	granulocyte colony-stimulating factor receptor binding	Csf3	IPI	PR:P09920	Mouse	PMID:2158861
Molecular Function	GO:0008083	growth factor activity	Csf3	IDA		Rat	PMID:8917083|RGD:1298819
Cellular Component	GO:0005615	extracellular space	Csf3	IDA		Rat	PMID:19732808|RGD:5133735
Biological Process	GO:0071345	cellular response to cytokine stimulus	CSF3	IDA		Human	PMID:23001182
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Csf3	IEP		Rat	PMID:19732808|RGD:5133735
Biological Process	GO:0035162	embryonic hemopoiesis	csf3a	IDA		Zfish	PMID:19139076
Biological Process	GO:0060218	hematopoietic stem cell differentiation	csf3a	IMP		Zfish	PMID:24128862
Biological Process	GO:0060218	hematopoietic stem cell differentiation	csf3b	IMP		Zfish	PMID:24128862
Biological Process	GO:0071425	hematopoietic stem cell proliferation	csf3a	IMP		Zfish	PMID:24128862
Biological Process	GO:0071425	hematopoietic stem cell proliferation	csf3b	IMP		Zfish	PMID:24128862
Biological Process	GO:0030225	macrophage differentiation	csf3a	IMP	ZFIN:ZDB-GENO-071109-4	Zfish	PMID:24128862
Biological Process	GO:0030225	macrophage differentiation	csf3b	IMP	ZFIN:ZDB-GENO-071109-4	Zfish	PMID:24128862
Biological Process	GO:0061515	myeloid cell development	csf3a	IMP		Zfish	PMID:24128862
Biological Process	GO:0061515	myeloid cell development	csf3b	IMP		Zfish	PMID:24128862
Biological Process	GO:0030099	myeloid cell differentiation	csf3a	IMP	ZFIN:ZDB-GENO-070118-1	Zfish	PMID:24128862
Biological Process	GO:0030099	myeloid cell differentiation	csf3b	IMP		Zfish	PMID:24128862
Biological Process	GO:1901215	negative regulation of neuron death	Csf3	IMP		Rat	PMID:19732808|RGD:5133735
Biological Process	GO:0030593	neutrophil chemotaxis	csf3b	IMP	ZFIN:ZDB-MRPHLNO-141212-1,ZFIN:ZDB-MRPHLNO-150828-4	Zfish	PMID:24890728
Biological Process	GO:0030223	neutrophil differentiation	csf3a	IMP	ZFIN:ZDB-GENO-071109-4	Zfish	PMID:24128862
Biological Process	GO:0030223	neutrophil differentiation	csf3b	IMP	ZFIN:ZDB-GENO-071109-4	Zfish	PMID:24128862
Biological Process	GO:2000251	positive regulation of actin cytoskeleton reorganization	CSF3	IDA		Human	PMID:23001182
Biological Process	GO:0030838	positive regulation of actin filament polymerization	CSF3	IDA		Human	PMID:23001182
Biological Process	GO:0008284	positive regulation of cell population proliferation	Csf3	IDA		Rat	PMID:8917083|RGD:1298819
Biological Process	GO:0051091	positive regulation of DNA-binding transcription factor activity	CSF3	IDA		Human	PMID:23001182
Biological Process	GO:0045639	positive regulation of myeloid cell differentiation	Csf3	IGI	MGI:MGI:1345151	Mouse	PMID:24216483
Biological Process	GO:0033138	positive regulation of peptidyl-serine phosphorylation	CSF3	IDA		Human	PMID:23001182
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	CSF3	IDA		Human	PMID:23001182
Biological Process	GO:0014068	positive regulation of phosphatidylinositol 3-kinase signaling	CSF3	IDA		Human	PMID:23001182
Biological Process	GO:0032092	positive regulation of protein binding	CSF3	IDA		Human	PMID:23001182
Biological Process	GO:0051897	positive regulation of protein kinase B signaling	CSF3	IDA		Human	PMID:23001182
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	CSF3	IDA		Human	PMID:23001182
Biological Process	GO:0045471	response to ethanol	Csf3	IEP		Rat	PMID:9835289|RGD:11039473

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern