Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes COL5A2
  • Mouse genes Col5a2
  • Rat genes Col5a2
  • Zfish genes col5a2a,col5a2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Col5a2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0030020	extracellular matrix structural constituent conferring tensile strength	COL5A2	HDA		Human	PMID:28344315
Molecular Function	GO:0046332	SMAD binding	Col5a2	IPI	PR:Q8BUN5	Mouse	PMID:14559231
Molecular Function	GO:0046332	SMAD binding	Col5a2	IPI	PR:O35253	Mouse	PMID:14559231
Molecular Function	GO:0046332	SMAD binding	Col5a2	IPI	PR:P97471	Mouse	PMID:14559231
Cellular Component	GO:0005581	collagen trimer	Col5a2	IDA		Mouse	PMID:7704020
Cellular Component	GO:0005588	collagen type V trimer	COL5A2	IMP		Human	PMID:9425231
Cellular Component	GO:0005588	collagen type V trimer	COL5A2	IMP		Human	PMID:9783710
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL5A2	HDA		Human	PMID:27068509
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL5A2	HDA		Human	PMID:27559042
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL5A2	HDA		Human	PMID:28327460
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL5A2	HDA		Human	PMID:28344315
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL5A2	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	COL5A2	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Col5a2	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Col5a2	HDA		Mouse	MGI:MGI:5582867|PMID:23658023
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Col5a2	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0005615	extracellular space	Col5a2	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Biological Process	GO:0071230	cellular response to amino acid stimulus	Col5a2	IDA		Mouse	PMID:20548288
Biological Process	GO:0030199	collagen fibril organization	COL5A2	IMP		Human	PMID:9425231
Biological Process	GO:0030199	collagen fibril organization	Col5a2	IMP		Mouse	MGI:MGI:3047505|PMID:15199158
Biological Process	GO:0048592	eye morphogenesis	COL5A2	IMP		Human	PMID:16431952
Biological Process	GO:1903225	negative regulation of endodermal cell differentiation	COL5A2	IDA		Human	PMID:23154389
Biological Process	GO:0001503	ossification	Col5a2	IEP		Rat	PMID:9822201|RGD:70694
Biological Process	GO:0001501	skeletal system development	Col5a2	IMP	MGI:MGI:2152946	Mouse	PMID:7704020
Biological Process	GO:0043588	skin development	COL5A2	IMP		Human	PMID:9425231
Biological Process	GO:0043588	skin development	Col5a2	IMP		Mouse	MGI:MGI:3047505|PMID:15199158

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern